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Molecular Basis for CPC-Sgo1 Interaction: Implications for Centromere Localisation and Function of t...

Molecular Basis for CPC-Sgo1 Interaction: Implications for Centromere Localisation and Function of t...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2565732630

Molecular Basis for CPC-Sgo1 Interaction: Implications for Centromere Localisation and Function of the CPC

About this item

Full title

Molecular Basis for CPC-Sgo1 Interaction: Implications for Centromere Localisation and Function of the CPC

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-08

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The Chromosomal Passenger Complex (CPC; consisting of Borealin, Survivin, INCENP and Aurora B kinase) and Shugoshin 1 (Sgo1) are key regulators of chromosome bi-orientation, a process essential for error-free chromosome segregation. Their functions rely on their ability to associate with centromeres. Two histone phosphorylations, histone H3 Thr3 (H...

Alternative Titles

Full title

Molecular Basis for CPC-Sgo1 Interaction: Implications for Centromere Localisation and Function of the CPC

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2565732630

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2565732630

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.08.27.457910