Age-related differences in immune dynamics during SARS-CoV-2 infection in rhesus macaques
Age-related differences in immune dynamics during SARS-CoV-2 infection in rhesus macaques
About this item
Full title
Author / Creator
Speranza, Emily , Purushotham, Jyothi N , Port, Julia Rebecca , Schwarz, Benjamin , Flagg, Meaghan , Williamson, Brandi N , Feldmann, Friederike , Singh, Manmeet , Perez-Perez, Lizzette , Sturdevant, Gail L , Roberts, Lydia M , Carmody, Aaron , Schulz, Jonathan E , Neeltje Van Doremalen , Okumura, Atsushi , Lovaglio, Jamie , Hanley, Patrick , Shaia, Carl , Germain, Ron , Best, Sonja , Munster, Vincent , Bosio, Catharine and De Wit, Emmie
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Advanced age is a key predictor of severe COVID-19. To gain insight into this relationship, particularly with respect to immune responses, we utilized the rhesus macaque model of SARS-CoV-2 infection. Two cohorts of eight older (16-23 years) and eight younger (3-5 years) rhesus macaques were inoculated with SARS-CoV-2. Animals were evaluated using...
Alternative Titles
Full title
Age-related differences in immune dynamics during SARS-CoV-2 infection in rhesus macaques
Authors, Artists and Contributors
Author / Creator
Purushotham, Jyothi N
Port, Julia Rebecca
Schwarz, Benjamin
Flagg, Meaghan
Williamson, Brandi N
Feldmann, Friederike
Singh, Manmeet
Perez-Perez, Lizzette
Sturdevant, Gail L
Roberts, Lydia M
Carmody, Aaron
Schulz, Jonathan E
Neeltje Van Doremalen
Okumura, Atsushi
Lovaglio, Jamie
Hanley, Patrick
Shaia, Carl
Germain, Ron
Best, Sonja
Munster, Vincent
Bosio, Catharine
De Wit, Emmie
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2570330115
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2570330115
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2021.09.08.459430
How to access this item
https://www.proquest.com/docview/2570330115?pq-origsite=primo&accountid=13902
