Limited evolution of the actionable metastatic cancer genome under therapeutic pressure
Limited evolution of the actionable metastatic cancer genome under therapeutic pressure
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Genomic profiling is critical for the identification of treatment options for patients with metastatic cancer, but it remains unclear how frequently this procedure should be repeated during the course of the disease. To address this, we analyzed whole-genome sequencing (WGS) data of 250 biopsy pairs, longitudinally collected over the treatment cour...
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Full title
Limited evolution of the actionable metastatic cancer genome under therapeutic pressure
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TN_cdi_proquest_journals_2572354103
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2572354103
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ISSN
1078-8956
E-ISSN
1546-170X
DOI
10.1038/s41591-021-01448-w
