Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrop...
Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity
About this item
Full title
Author / Creator
Di Conza, Giusy , Tsai, Chin-Hsien , Gallart-Ayala, Hector , Yu, Yi-Ru , Franco, Fabien , Zaffalon, Lea , Xie, Xin , Li, Xiaoyun , Xiao, Zhengtao , Raines, Lydia N. , Falquet, Maryline , Jalil, Antoine , Locasale, Jason W. , Percipalle, Piergiorgio , Masson, David , Huang, Stanley Ching-Cheng , Martinon, Fabio , Ivanisevic, Julijana and Ho, Ping-Chih
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Tumor-associated macrophages (TAMs) display pro-tumorigenic phenotypes for supporting tumor progression in response to microenvironmental cues imposed by tumor and stromal cells. However, the underlying mechanisms by which tumor cells instruct TAM behavior remain elusive. Here, we uncover that tumor-cell-derived glucosylceramide stimulated unconven...
Alternative Titles
Full title
Tumor-induced reshuffling of lipid composition on the endoplasmic reticulum membrane sustains macrophage survival and pro-tumorigenic activity
Authors, Artists and Contributors
Author / Creator
Tsai, Chin-Hsien
Gallart-Ayala, Hector
Yu, Yi-Ru
Franco, Fabien
Zaffalon, Lea
Xie, Xin
Li, Xiaoyun
Xiao, Zhengtao
Raines, Lydia N.
Falquet, Maryline
Jalil, Antoine
Locasale, Jason W.
Percipalle, Piergiorgio
Masson, David
Huang, Stanley Ching-Cheng
Martinon, Fabio
Ivanisevic, Julijana
Ho, Ping-Chih
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2587482301
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2587482301
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-021-01047-4
