Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model...
Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimers disease
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Synapse loss is associated with cognitive decline in Alzheimers disease (AD) and owing to their plastic nature, synapses are an ideal target for therapeutic intervention. Oligomeric amyloid beta (Ab) around amyloid plaques is known to contribute to synapse loss in mouse models and is associated with synapse loss in human AD brain tissue, but the me...
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Reducing voltage-dependent potassium channel Kv3.4 levels ameliorates synapse loss in a mouse model of Alzheimers disease
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TN_cdi_proquest_journals_2602340095
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2602340095
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2692-8205
DOI
10.1101/2021.11.24.469829
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https://www.proquest.com/docview/2602340095?pq-origsite=primo&accountid=13902