The GFP thermal shift assay for screening ligand and lipid interactions to solute carrier transporte...
The GFP thermal shift assay for screening ligand and lipid interactions to solute carrier transporters
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
Solute carrier (SLC) transporters represent the second-largest fraction of the membrane proteome after G-protein-coupled receptors, but have been underutilized as drug targets and the function of many members of this family is still unknown. They are technically challenging to work with as they are difficult to express and highly dynamic, making th...
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Full title
The GFP thermal shift assay for screening ligand and lipid interactions to solute carrier transporters
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TN_cdi_proquest_journals_2605769934
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2605769934
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ISSN
1754-2189
E-ISSN
1750-2799
DOI
10.1038/s41596-021-00619-w
