A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
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Author / Creator
Judd, Jonathan , Graham, Sarah E , Wells, Andrew , Hilliard, Austin T , Xue, Chao , Helgadottir, Anna , Holm, Hilma , Han, Sohee , Sakaue, Saori , Jennifer Allen Pacheco , Feng, Qiping , Lin, Kuang , Zhao, Wei , Brown, Michael R , Yin, Xianyong , Luan, Jian'an , Jing-Hua, Zhao , Hye-Mi Jang , Hottenga, Jouke Jan , Haworth, Simon , Wielscher, Matthias , Sattar, Naveed , Munz, Matthias , Yang, Bin , Zmuda, Joseph M , Feitosa, Mary F , Benjamins, Jan W , Delgado, Graciela E , Fernandez-Lopez, Juan Carlos , Timmers, Paul Rhj , Arbeeva, Liubov , Spracklen, Cassandra N , Loukola, Anu , Ya Xing Wang , Nutile, Teresa , Sung, Yun Ju , Kentistou, Katherine A , Bielak, Lawrence F , Peter J Van Der Most , Sander W Van Der Laan , Kumaraswamy Naidu Chitrala , Freitag-Wolf, Sandra , Southam, Lorraine , Wang, Carol A , Shih-Yi, Lin , Terzikhan, Natalie , Kawaguchi, Takahisa , Campbell, Harry , Niinikoski, Harri , Eung Kweon Kim , Hewitt, Alex W , Kahonen, Mika , Pennell, Craig E , Franke, Andre , Koh, Woon-Puay , Jeong-Taek Woo , Biino, Ginevra , Dedoussis, George , Schulze, Matthias B , Munroe, Patricia B , Jonas, Jost B , De Silva, H Janaka , Wu, Jer-Yuarn , Den Hollander, Anneke I , Bharadwaj, Dwaipayan , Wilson, James G , Orozco, Lorena , nage, Myriam , Reilly, Dermot F , Lu, Fan , Hishigaki, Haretsugu , Gudnason, Vilmundur , Tardif, Jean-Claude , Hart, Leen M T , Loos, Ruth Jf , Christensen, Kaare , Kronenberg, Florian , Kutalik, Zoltan , Rotter, Jerome I , Neville, Matt J , Tien-Yin, Wong , Khor, Chiea Chuen , Li, Hengtong , Hattersley, Andrew T , Gordon-Larsen, Penny , Huang, Wei , Tuomilehto, Jaakko , Ingelsson, Erik , Hazelhurst, Scott , Saleheen, Danish , Kooperberg, Charles , Tamiya, Gen , Van Heel, David A , Jarvik, Gail P , Salomaa, Veikko , Murakami, Yoshinori , Zhang, Jifeng , Lynch, Julie A , Grant, Struan Fa and Morris, Andrew P
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
A major challenge of genome-wide association studies (GWAS) is to translate phenotypic associations into biological insights. Here, we integrate a large GWAS on blood lipids involving 1.6 million individuals from five ancestries with a wide array of functional genomic datasets to discover regulatory mechanisms underlying lipid associations. We firs...
Alternative Titles
Full title
A multi-layer functional genomic analysis to understand noncoding genetic variation in lipids
Authors, Artists and Contributors
Author / Creator
Graham, Sarah E
Wells, Andrew
Hilliard, Austin T
Xue, Chao
Helgadottir, Anna
Holm, Hilma
Han, Sohee
Sakaue, Saori
Jennifer Allen Pacheco
Feng, Qiping
Lin, Kuang
Zhao, Wei
Brown, Michael R
Yin, Xianyong
Luan, Jian'an
Jing-Hua, Zhao
Hye-Mi Jang
Hottenga, Jouke Jan
Haworth, Simon
Wielscher, Matthias
Sattar, Naveed
Munz, Matthias
Yang, Bin
Zmuda, Joseph M
Feitosa, Mary F
Benjamins, Jan W
Delgado, Graciela E
Fernandez-Lopez, Juan Carlos
Timmers, Paul Rhj
Arbeeva, Liubov
Spracklen, Cassandra N
Loukola, Anu
Ya Xing Wang
Nutile, Teresa
Sung, Yun Ju
Kentistou, Katherine A
Bielak, Lawrence F
Peter J Van Der Most
Sander W Van Der Laan
Kumaraswamy Naidu Chitrala
Freitag-Wolf, Sandra
Southam, Lorraine
Wang, Carol A
Shih-Yi, Lin
Terzikhan, Natalie
Kawaguchi, Takahisa
Campbell, Harry
Niinikoski, Harri
Eung Kweon Kim
Hewitt, Alex W
Kahonen, Mika
Pennell, Craig E
Franke, Andre
Koh, Woon-Puay
Jeong-Taek Woo
Biino, Ginevra
Dedoussis, George
Schulze, Matthias B
Munroe, Patricia B
Jonas, Jost B
De Silva, H Janaka
Wu, Jer-Yuarn
Den Hollander, Anneke I
Bharadwaj, Dwaipayan
Wilson, James G
Orozco, Lorena
nage, Myriam
Reilly, Dermot F
Lu, Fan
Hishigaki, Haretsugu
Gudnason, Vilmundur
Tardif, Jean-Claude
Hart, Leen M T
Loos, Ruth Jf
Christensen, Kaare
Kronenberg, Florian
Kutalik, Zoltan
Rotter, Jerome I
Neville, Matt J
Tien-Yin, Wong
Khor, Chiea Chuen
Li, Hengtong
Hattersley, Andrew T
Gordon-Larsen, Penny
Huang, Wei
Tuomilehto, Jaakko
Ingelsson, Erik
Hazelhurst, Scott
Saleheen, Danish
Kooperberg, Charles
Tamiya, Gen
Van Heel, David A
Jarvik, Gail P
Salomaa, Veikko
Murakami, Yoshinori
Zhang, Jifeng
Lynch, Julie A
Grant, Struan Fa
Morris, Andrew P
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2607925211
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2607925211
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2021.12.07.470215
How to access this item
https://www.proquest.com/docview/2607925211?pq-origsite=primo&accountid=13902
