Intranasal immunization with a vaccinia virus vaccine vector expressing pre-fusion stabilized SARS-C...
Intranasal immunization with a vaccinia virus vaccine vector expressing pre-fusion stabilized SARS-CoV-2 spike fully protected mice against lethal challenge with the heavily mutated mouse-adapted SARS2-N501YMA30 strain of SARS-CoV-2
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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The Omicron SARS-CoV-2 variant has been designated a variant of concern because its spike protein is heavily mutated. In particular, Omicron spike is mutated at 5 positions (K417, N440, E484, Q493 and N501) that have been associated with escape from neutralizing antibodies induced by either infection with or immunization against the early Washingto...
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Full title
Intranasal immunization with a vaccinia virus vaccine vector expressing pre-fusion stabilized SARS-CoV-2 spike fully protected mice against lethal challenge with the heavily mutated mouse-adapted SARS2-N501YMA30 strain of SARS-CoV-2
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TN_cdi_proquest_journals_2607925534
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2607925534
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E-ISSN
2692-8205
DOI
10.1101/2021.12.06.471483
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https://www.proquest.com/docview/2607925534?pq-origsite=primo&accountid=13902
