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Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization...

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2615531957

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ

About this item

Full title

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ

Publisher

London: Nature Publishing Group UK

Journal title

Oncogene, 2017-08, Vol.36 (32), p.4573-4584

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Recent evidences suggest that stearoyl-CoA-desaturase 1 (SCD1), the enzyme involved in monounsaturated fatty acids synthesis, has a role in several cancers. We previously demonstrated that SCD1 is important in lung cancer stem cells survival and propagation. In this article, we first show, using primary cell cultures from human lung adenocarcinoma,...

Alternative Titles

Full title

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2615531957

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2615531957

Other Identifiers

ISSN

0950-9232

E-ISSN

1476-5594

DOI

10.1038/onc.2017.75

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