Myeloid-biased HSC require Semaphorin 4A from the bone marrow niche for self-renewal under stress an...
Myeloid-biased HSC require Semaphorin 4A from the bone marrow niche for self-renewal under stress and life-long persistence
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Author / Creator
Dorsa Toghani , Zeng, Sharon , Mahammadov, Elmir , Crosse, Edie I , Seyedhassantehrani, Negar , Burns, Christian , Gravano, David , Radtke, Stefan , Hans-Peter Kiem , Rodriguez, Sonia , Carlesso, Nadia , Amogh Pradeep , Wilson, Nicola K , Kinston, Sarah J , Gottgens, Berthold , Nerlov, Claus , Pietras, Eric , Mesnieres, Marion , Maes, Christa , Kumanogoh, Atsushi , Worzfeld, Thomas , Kharchenko, Peter , Scialdone, Antonio , Spencer, Joel A and Silberstein, Lev
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Tissue stem cells are hierarchically organized. Those that are most primitive serve as key drivers of regenerative response but the signals that selectively preserve their functional integrity are largely unknown. Here, we identify a secreted factor, Semaphorin 4A (Sema4A), as a specific regulator of myeloid-biased hematopoietic stem cells (myHSC),...
Alternative Titles
Full title
Myeloid-biased HSC require Semaphorin 4A from the bone marrow niche for self-renewal under stress and life-long persistence
Authors, Artists and Contributors
Author / Creator
Zeng, Sharon
Mahammadov, Elmir
Crosse, Edie I
Seyedhassantehrani, Negar
Burns, Christian
Gravano, David
Radtke, Stefan
Hans-Peter Kiem
Rodriguez, Sonia
Carlesso, Nadia
Amogh Pradeep
Wilson, Nicola K
Kinston, Sarah J
Gottgens, Berthold
Nerlov, Claus
Pietras, Eric
Mesnieres, Marion
Maes, Christa
Kumanogoh, Atsushi
Worzfeld, Thomas
Kharchenko, Peter
Scialdone, Antonio
Spencer, Joel A
Silberstein, Lev
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2619060863
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2619060863
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2022.01.12.476097
How to access this item
https://www.proquest.com/docview/2619060863?pq-origsite=primo&accountid=13902