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Reactive Astrocytes Contribute to Alzheimer's Disease-Related Neurotoxicity and Synaptotoxicity in a...

Reactive Astrocytes Contribute to Alzheimer's Disease-Related Neurotoxicity and Synaptotoxicity in a...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2621811224

Reactive Astrocytes Contribute to Alzheimer's Disease-Related Neurotoxicity and Synaptotoxicity in a Neuron-Astrocyte Co-culture Assay

About this item

Full title

Reactive Astrocytes Contribute to Alzheimer's Disease-Related Neurotoxicity and Synaptotoxicity in a Neuron-Astrocyte Co-culture Assay

Publisher

Switzerland: Frontiers Research Foundation

Journal title

Frontiers in cellular neuroscience, 2022-01, Vol.15, p.739411-739411

Language

English

Formats

Publication information

Publisher

Switzerland: Frontiers Research Foundation

More information

Scope and Contents

Contents

Pathological hallmarks of Alzheimer's disease (AD) include deposition and accumulation of amyloid- β (Aβ), neurofibrillary tangle formation, and neuronal loss. Pathogenesis of presymptomatic disease stages remains elusive, although studies suggest that the early structural and functional alterations likely occur at neuronal dendritic spines. Presym...

Alternative Titles

Full title

Reactive Astrocytes Contribute to Alzheimer's Disease-Related Neurotoxicity and Synaptotoxicity in a Neuron-Astrocyte Co-culture Assay

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2621811224

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2621811224

Other Identifiers

ISSN

1662-5102

E-ISSN

1662-5102

DOI

10.3389/fncel.2021.739411

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