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Ex vivo and in vivo evidence that cigarette smoke-exposed T regulatory cells impair host immunity ag...

Ex vivo and in vivo evidence that cigarette smoke-exposed T regulatory cells impair host immunity ag...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2621937288

Ex vivo and in vivo evidence that cigarette smoke-exposed T regulatory cells impair host immunity against Mycobacterium tuberculosis

About this item

Full title

Ex vivo and in vivo evidence that cigarette smoke-exposed T regulatory cells impair host immunity against Mycobacterium tuberculosis

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2022-01

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

A strong epidemiologic link exists between exposure to cigarette smoke (CS) and increased susceptibility to tuberculosis (TB). In vitro macrophage and in vivo murine studies showed that CS and nicotine impair host-protective immune cells against Mycobacterium tuberculosis (MTB) infection. However, little is known about how CS may affect immunosuppr...

Alternative Titles

Full title

Ex vivo and in vivo evidence that cigarette smoke-exposed T regulatory cells impair host immunity against Mycobacterium tuberculosis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2621937288

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2621937288

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2022.01.20.477097