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Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition

Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2645307027

Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition

About this item

Full title

Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition

Publisher

Switzerland: Frontiers Research Foundation

Journal title

Frontiers in aging neuroscience, 2022-03, Vol.14, p.854031-854031

Language

English

Formats

Publication information

Publisher

Switzerland: Frontiers Research Foundation

More information

Scope and Contents

Contents

We undertook longitudinal β-amyloid positron emission tomography (Aβ-PET) imaging as a translational tool for monitoring of chronic treatment with the peroxisome proliferator-activated receptor gamma (PPARγ) agonist pioglitazone in Aβ model mice. We thus tested the hypothesis this treatment would rescue from increases of the Aβ-PET signal while pro...

Alternative Titles

Full title

Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2645307027

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2645307027

Other Identifiers

ISSN

1663-4365

E-ISSN

1663-4365

DOI

10.3389/fnagi.2022.854031

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