A single nucleotide polymorphism-based formula to predict the risk of propofol TCI concentration bei...
A single nucleotide polymorphism-based formula to predict the risk of propofol TCI concentration being over 4 µg mL−1 at the time of loss of consciousness
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Author / Creator
Zheng, Zhuoling , Xue, Faling , Wang, Haini , He, Yongqi , Zhang, Lingyi , Ma, Wudi , Zhang, Caibin , Guan, Yanping , Ye, Fang , Wen, Yongzi , Li, Xiaoyan , Huang, Min , Huang, Wenqi , Wang, Zhongxing and Li, Jiali
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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Scope and Contents
Contents
We aim to develop a formula based on single nucleotide polymorphisms (SNPs) to predict whether the propofol target-controlled infusion (TCI) concentration would be over 4 μg mL
−1
at the time of loss of consciousness (LOC). We recruited 184 patients undergoing thyroid or breast surgeries with propofol anaesthesia. A total of 48 SNPs of
CYP...
Alternative Titles
Full title
A single nucleotide polymorphism-based formula to predict the risk of propofol TCI concentration being over 4 µg mL−1 at the time of loss of consciousness
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Record Identifier
TN_cdi_proquest_journals_2646016144
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2646016144
Other Identifiers
ISSN
1470-269X
E-ISSN
1473-1150
DOI
10.1038/s41397-021-00263-3
