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Single-cell transcriptomics reveal hyperacute cytokine and immune checkpoint axis in patients with p...

Single-cell transcriptomics reveal hyperacute cytokine and immune checkpoint axis in patients with p...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2647051371

Single-cell transcriptomics reveal hyperacute cytokine and immune checkpoint axis in patients with poor neurological outcomes after cardiac arrest

About this item

Full title

Single-cell transcriptomics reveal hyperacute cytokine and immune checkpoint axis in patients with poor neurological outcomes after cardiac arrest

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2022-04

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Neurological injury is a major driver of mortality among patients hospitalized after cardiac arrest (CA). The early systemic inflammatory response after CA is associated with neurological injury and mortality but remains poorly defined. We determine the innate immune network induced by clinical CA at single-cell resolution. Immune cell states diver...

Alternative Titles

Full title

Single-cell transcriptomics reveal hyperacute cytokine and immune checkpoint axis in patients with poor neurological outcomes after cardiac arrest

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2647051371

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2647051371

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2022.04.04.487033