A positive feedback loop controls Toxoplasma chronic differentiation
A positive feedback loop controls Toxoplasma chronic differentiation
About this item
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Successful infection strategies must balance pathogen amplification and persistence. In Toxoplasma gondii, this is accomplished through differentiation into dedicated cyst-forming chronic stages that avoid clearance by the host immune system. The transcription factor BFD1 is both necessary and sufficient for stage conversion; however, its regulatio...
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Full title
A positive feedback loop controls Toxoplasma chronic differentiation
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TN_cdi_proquest_journals_2647467684
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2647467684
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E-ISSN
2692-8205
DOI
10.1101/2022.04.06.487076
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https://www.proquest.com/docview/2647467684?pq-origsite=primo&accountid=13902
