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AI-guided screen identifies probucol-mediated mitophagy enhancement through modulation of lipid drop...

AI-guided screen identifies probucol-mediated mitophagy enhancement through modulation of lipid drop...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2667085110

AI-guided screen identifies probucol-mediated mitophagy enhancement through modulation of lipid droplets

About this item

Full title

AI-guided screen identifies probucol-mediated mitophagy enhancement through modulation of lipid droplets

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2022-05

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Failures in mitophagy, a process by which damaged mitochondria are cleared, results in neurodegeneration, while enhancing mitophagy promotes the survival of dopaminergic neurons. Using an artificial intelligence platform, we employed a natural language processing approach to evaluate the semantic similarity of candidate molecules to a set of well-e...

Alternative Titles

Full title

AI-guided screen identifies probucol-mediated mitophagy enhancement through modulation of lipid droplets

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2667085110

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2667085110

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2022.05.18.492560