MrgprA3-expressing pruriceptors drive pruritogen-induced alloknesis through mechanosensitive Piezo2...
MrgprA3-expressing pruriceptors drive pruritogen-induced alloknesis through mechanosensitive Piezo2 channel
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Author / Creator
Lu, Ping , Zhao, Yonghui , Xie, Zili , Dong, Xinzhong , Wu, Gregory , Kim, Brian , Feng, Jing and Hu, Hongzhen
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Although touch and itch are coded by distinct neuronal populations, light touch also provokes itch in the presence of exogenous pruritogens, resulting in a phenomenon called alloknesis. However, the cellular and molecular mechanisms underlying the initiation of pruritogen-induced mechanical itch sensitization are poorly understood. Here we show tha...
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Full title
MrgprA3-expressing pruriceptors drive pruritogen-induced alloknesis through mechanosensitive Piezo2 channel
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Record Identifier
TN_cdi_proquest_journals_2681058812
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2681058812
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E-ISSN
2692-8205
DOI
10.1101/2022.06.22.497257
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https://www.proquest.com/docview/2681058812?pq-origsite=primo&accountid=13902