Integrating pharmacogenomics data-driven prediction with bulk and single-cell RNAseq to demonstrate...
Integrating pharmacogenomics data-driven prediction with bulk and single-cell RNAseq to demonstrate the efficacy of an NAMPT inhibitor against aggressive, taxane-resistant, and stem-like cells in lethal prostate cancer
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Metastatic prostate cancer is the second leading cause of cancer deaths in US men. Resistance to standard medical castration and secondary taxane based chemotherapy is nearly universal. Further, presence of cancer stem like cells (EMT/epithelial to mesenchymal transdifferentiation) and neuroendocrine PCa (NEPC) subtypes significantly contribute to...
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Full title
Integrating pharmacogenomics data-driven prediction with bulk and single-cell RNAseq to demonstrate the efficacy of an NAMPT inhibitor against aggressive, taxane-resistant, and stem-like cells in lethal prostate cancer
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TN_cdi_proquest_journals_2692866460
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2692866460
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E-ISSN
2692-8205
DOI
10.1101/2022.07.20.500378
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https://www.proquest.com/docview/2692866460?pq-origsite=primo&accountid=13902
