The clinically relevant CYP2C83 and CYP2C92 haplotype is inherited from Neandertals
The clinically relevant CYP2C83 and CYP2C92 haplotype is inherited from Neandertals
About this item
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Author / Creator
Publisher
London: Springer Science and Business Media LLC
Journal title
Language
English
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Publisher
London: Springer Science and Business Media LLC
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Scope and Contents
Contents
Genetic variation in genes encoding cytochrome P450 enzymes influences the metabolism of drugs and endogenous compounds. The locus containing the cytochrome genes
CYP2C8
and
CYP2C9
on chromosome 10 exhibits linkage disequilibrium between the
CYP2C8*3
and
CYP2C9*2
alleles, forming a haplotype of ~300 kilobases. This haplotype...
Alternative Titles
Full title
The clinically relevant CYP2C83 and CYP2C92 haplotype is inherited from Neandertals
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TN_cdi_proquest_journals_2700172283
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2700172283
Other Identifiers
ISSN
1470-269X
E-ISSN
1473-1150
DOI
10.1038/s41397-022-00284-6
