Plasma neurofilament light levels as a novel biomarker for neurological involve- ment in Wilson’s di...
Plasma neurofilament light levels as a novel biomarker for neurological involve- ment in Wilson’s disease
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London: BMJ Publishing Group Ltd
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Language
English
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London: BMJ Publishing Group Ltd
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BackgroundSerum and urine copper levels are used to monitor chelation therapy for Wilson’s disease (WD) but do not reflect neurological involvement. Biomarkers of end-organ damage are needed to optimise chelation therapy and prepare for clinical trials for gene therapy.MethodsWe measured neurofilament light (NfL) levels in plasma samples, Unified W...
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Plasma neurofilament light levels as a novel biomarker for neurological involve- ment in Wilson’s disease
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TN_cdi_proquest_journals_2708262419
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2708262419
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ISSN
0022-3050
E-ISSN
1468-330X
DOI
10.1136/jnnp-2022-ABN.17
