CDK11 regulates pre-mRNA splicing by phosphorylation of SF3B1
CDK11 regulates pre-mRNA splicing by phosphorylation of SF3B1
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London: Nature Publishing Group UK
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Language
English
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London: Nature Publishing Group UK
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Contents
RNA splicing, the process of intron removal from pre-mRNA, is essential for the regulation of gene expression. It is controlled by the spliceosome, a megadalton RNA–protein complex that assembles de novo on each pre-mRNA intron through an ordered assembly of intermediate complexes
1
,
2
. Spliceosome activation is a major control step t...
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Full title
CDK11 regulates pre-mRNA splicing by phosphorylation of SF3B1
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TN_cdi_proquest_journals_2717340816
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2717340816
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ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-022-05204-z
