Absence of microbiome in chronic infections impairs viral control without affecting CD8 T cell funct...
Absence of microbiome in chronic infections impairs viral control without affecting CD8 T cell function
About this item
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Prolonged antigen exposure in chronic viral infections reduces the effector capacity of cytotoxic T cells - a phenomenon known as T cell exhaustion. High viral titer, strong TCR stimulation, and high antigen concentrations associated with strong inflammatory signals are known factors that promote the development of T cell exhaustion. A largely unex...
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Full title
Absence of microbiome in chronic infections impairs viral control without affecting CD8 T cell function
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TN_cdi_proquest_journals_2722609683
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2722609683
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DOI
10.1101/2022.10.03.510696
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https://www.proquest.com/docview/2722609683?pq-origsite=primo&accountid=13902
