RNF43 mutations predict response to anti-BRAF/EGFR combinatory therapies in BRAFV600E metastatic col...
RNF43 mutations predict response to anti-BRAF/EGFR combinatory therapies in BRAFV600E metastatic colorectal cancer
About this item
Full title
Author / Creator
Elez, Elena , Ros, Javier , Fernández, Jose , Villacampa, Guillermo , Moreno-Cárdenas, Ana Belén , Arenillas, Carlota , Bernatowicz, Kinga , Comas, Raquel , Li, Shanshan , Kodack, David Philip , Fasani, Roberta , Garcia, Ariadna , Gonzalo-Ruiz, Javier , Piris-Gimenez, Alejandro , Nuciforo, Paolo , Kerr, Grainne , Intini, Rossana , Montagna, Aldo , Germani, Marco Maria , Randon, Giovanni , Vivancos, Ana , Smits, Ron , Graus, Diana , Perez-Lopez, Raquel , Cremolini, Chiara , Lonardi, Sara , Pietrantonio, Filippo , Dienstmann, Rodrigo , Tabernero, Josep and Toledo, Rodrigo A.
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Anti-BRAF/EGFR therapy was recently approved for the treatment of metastatic
BRAF
V600E
colorectal cancer (mCRC
BRAF-V600E
). However, a large fraction of patients do not respond, underscoring the need to identify molecular determinants of treatment response. Using whole-exome sequencing in a discovery cohort of patients with mCRC
Alternative Titles
Full title
RNF43 mutations predict response to anti-BRAF/EGFR combinatory therapies in BRAFV600E metastatic colorectal cancer
Authors, Artists and Contributors
Author / Creator
Ros, Javier
Fernández, Jose
Villacampa, Guillermo
Moreno-Cárdenas, Ana Belén
Arenillas, Carlota
Bernatowicz, Kinga
Comas, Raquel
Li, Shanshan
Kodack, David Philip
Fasani, Roberta
Garcia, Ariadna
Gonzalo-Ruiz, Javier
Piris-Gimenez, Alejandro
Nuciforo, Paolo
Kerr, Grainne
Intini, Rossana
Montagna, Aldo
Germani, Marco Maria
Randon, Giovanni
Vivancos, Ana
Smits, Ron
Graus, Diana
Perez-Lopez, Raquel
Cremolini, Chiara
Lonardi, Sara
Pietrantonio, Filippo
Dienstmann, Rodrigo
Tabernero, Josep
Toledo, Rodrigo A.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2724089553
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2724089553
Other Identifiers
ISSN
1078-8956,1546-170X
E-ISSN
1546-170X
DOI
10.1038/s41591-022-01976-z
