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The KEYNOTE-811 trial of dual PD-1 and HER2 blockade in HER2-positive gastric cancer
Author / Creator:Janjigian, Yelena Y. ; Kawazoe, Akihito ; Yañez, Patricio ; Li, Ning ; Lonardi, Sara ; Kolesnik, Oleksii ; Barajas, Olga ; Bai, Yuxian ; Shen, Lin ; Tang, Yong ; Wyrwicz, Lucjan S. ; Xu, Jianming ; Shitara, Kohei ; Qin, Shukui ; Van Cutsem, Eric ; Tabernero, Josep ; Li, Lie ; Shah, Sukrut ; Bhagia, Pooja ; Chung, Hyun Cheol
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2021-12, Vol.600 (7890), p.727-730
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Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal Cancer
Author / Creator:Kopetz, Scott ; Grothey, Axel ; Yaeger, Rona ; Van Cutsem, Eric ; Desai, Jayesh ; Yoshino, Takayuki ; Wasan, Harpreet ; Ciardiello, Fortunato ; Loupakis, Fotios ; Hong, Yong Sang ; Steeghs, Neeltje ; Guren, Tormod K ; Arkenau, Hendrik-Tobias ; Garcia-Alfonso, Pilar ; Pfeiffer, Per ; Orlov, Sergey ; Lonardi, Sara ; Elez, Elena ; Kim, Tae-Won ; Schellens, Jan H.M ; Guo, Christina ; Krishnan, Asha ; Dekervel, Jeroen ; Morris, Van ; Calvo Ferrandiz, Aitana ; Tarpgaard, L.S ; Braun, Michael ; Gollerkeri, Ashwin ; Keir, Christopher ; Maharry, Kati ; Pickard, Michael ; Christy-Bittel, Janna ; Anderson, Lisa ; Sandor, Victor ; Tabernero, Josep
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2019-10, Vol.381 (17), p.1632-1643
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Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study
Author / Creator:Overman, Michael J, Dr ; McDermott, Ray, MD ; Leach, Joseph L, MD ; Lonardi, Sara, MD ; Lenz, Heinz-Josef, MD ; Morse, Michael A, MD ; Desai, Jayesh, MBBS ; Hill, Andrew, MBBS ; Axelson, Michael, MD ; Moss, Rebecca A, MD ; Goldberg, Monica V, MD ; Cao, Z Alexander, PhD ; Ledeine, Jean-Marie, MSc ; Maglinte, Gregory A, PhD ; Kopetz, Scott, MD ; André, Thierry, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2017-09, Vol.18 (9), p.1182-1191
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Upfront FOLFOXIRI plus bevacizumab and reintroduction after progression versus mFOLFOX6 plus bevacizumab followed by FOLFIRI plus bevacizumab in the treatment of patients with metastatic colorectal ca...
Author / Creator:Cremolini, Chiara, MD ; Antoniotti, Carlotta, MD ; Rossini, Daniele, MD ; Lonardi, Sara, MD ; Loupakis, Fotios, MD ; Pietrantonio, Filippo, MD ; Bordonaro, Roberto, MD ; Latiano, Tiziana Pia, MD ; Tamburini, Emiliano, MD ; Santini, Daniele, Prof ; Passardi, Alessandro, MD ; Marmorino, Federica, MD ; Grande, Roberta, MD ; Aprile, Giuseppe, MD ; Zaniboni, Alberto, MD ; Murgioni, Sabina, MD ; Granetto, Cristina, MD ; Buonadonna, Angela, MD ; Moretto, Roberto, MD ; Corallo, Salvatore, MD ; Cordio, Stefano, MD ; Antonuzzo, Lorenzo, MD ; Tomasello, Gianluca, MD ; Masi, Gianluca, Prof ; Ronzoni, Monica, MD ; Di Donato, Samantha, MD ; Carlomagno, Chiara, Prof ; Clavarezza, Matteo, MD ; Ritorto, Giuliana, MD ; Mambrini, Andrea, MD ; Roselli, Mario, Prof ; Cupini, Samanta, MD ; Mammoliti, Serafina, MD ; Fenocchio, Elisabetta, MD ; Corgna, Enrichetta, MD ; Zagonel, Vittorina, MD ; Fontanini, Gabriella, Prof ; Ugolini, Clara, MD ; Boni, Luca, MD ; Falcone, Alfredo, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2020-04, Vol.21 (4), p.497-507
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Upfront FOLFOXIRI plus bevacizumab with or without atezolizumab in the treatment of patients with metastatic colorectal cancer (AtezoTRIBE): a multicentre, open-label, randomised, controlled, phase 2...
Author / Creator:Antoniotti, Carlotta, MD ; Rossini, Daniele, MD ; Pietrantonio, Filippo, MD ; Catteau, Aurélie, PhD ; Salvatore, Lisa, PhD ; Lonardi, Sara, MD ; Boquet, Isabelle, PhD ; Tamberi, Stefano, PhD ; Marmorino, Federica, MD ; Moretto, Roberto, MD ; Ambrosini, Margherita, MD ; Tamburini, Emiliano, MD ; Tortora, Giampaolo, Prof ; Passardi, Alessandro, MD ; Bergamo, Francesca, MD ; Kassambara, Alboukadel, PhD ; Sbarrato, Thomas, PhD ; Morano, Federica, MD ; Ritorto, Giuliana, MD ; Borelli, Beatrice, MD ; Boccaccino, Alessandra, MD ; Conca, Veronica, MD ; Giordano, Mirella, PhD ; Ugolini, Clara, Prof ; Fieschi, Jacques, PhD ; Papadopulos, Alexia, PhD ; Massoué, Clémentine, BS ; Aprile, Giuseppe, MD ; Antonuzzo, Lorenzo, Prof ; Gelsomino, Fabio, MD ; Martinelli, Erika, Prof ; Pella, Nicoletta, MD ; Masi, Gianluca, Prof ; Fontanini, Gabriella, Prof ; Boni, Luca, MD ; Galon, Jérôme, PhD ; Cremolini, Chiara, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2022-07, Vol.23 (7), p.876-887
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Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, an...
Author / Creator:Tabernero, Josep, Dr ; Yoshino, Takayuki, MD ; Cohn, Allen Lee, MD ; Obermannova, Radka, MD ; Bodoky, Gyorgy, Prof ; Garcia-Carbonero, Rocio, MD ; Ciuleanu, Tudor-Eliade, Prof ; Portnoy, David C, MD ; Van Cutsem, Eric, Prof ; Grothey, Axel, MD ; Prausová, Jana, MD ; Garcia-Alfonso, Pilar, PhD ; Yamazaki, Kentaro, MD ; Clingan, Philip R, Prof ; Lonardi, Sara, MD ; Kim, Tae Won, Prof ; Simms, Lorinda, MS ; Chang, Shao-Chun, PhD ; Nasroulah, Federico, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2015-05, Vol.16 (5), p.499-508
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FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-l...
Author / Creator:Cremolini, Chiara, MD ; Loupakis, Fotios, PhD ; Antoniotti, Carlotta, MD ; Lupi, Cristiana, BSc ; Sensi, Elisa, PhD ; Lonardi, Sara, MD ; Mezi, Silvia, MD ; Tomasello, Gianluca, MD ; Ronzoni, Monica, MD ; Zaniboni, Alberto, MD ; Tonini, Giuseppe, Prof ; Carlomagno, Chiara, PhD ; Allegrini, Giacomo, MD ; Chiara, Silvana, MD ; D'Amico, Mauro, MD ; Granetto, Cristina, MD ; Cazzaniga, Marina, MD ; Boni, Luca, MD ; Fontanini, Gabriella, Prof ; Falcone, Alfredo, Prof
Publisher:England: Elsevier Limited
Journal title:The lancet oncology, 2015-10, Vol.16 (13), p.1306-1315
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Trastuzumab deruxtecan in patients in the USA and Europe with HER2-positive advanced gastric or gastroesophageal junction cancer with disease progression on or after a trastuzumab-containing regimen (...
Author / Creator:Van Cutsem, Eric, Prof ; di Bartolomeo, Maria, MD ; Smyth, Elizabeth, MD ; Chau, Ian, MD ; Park, Haeseong, MD ; Siena, Salvatore, Prof ; Lonardi, Sara, MD ; Wainberg, Zev A, MD ; Ajani, Jaffer, Prof ; Chao, Joseph, MD ; Janjigian, Yelena, MD ; Qin, Amy, PhD ; Singh, Jasmeet, MD ; Barlaskar, Ferdous, MD ; Kawaguchi, Yoshinori, MSc ; Ku, Geoffrey, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2023-07, Vol.24 (7), p.744-756
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The Pan-Immune-Inflammation Value is a new prognostic biomarker in metastatic colorectal cancer: results from a pooled-analysis of the Valentino and TRIBE first-line trials
Author / Creator:Fucà, Giovanni ; Guarini, Vincenzo ; Antoniotti, Carlotta ; Morano, Federica ; Moretto, Roberto ; Corallo, Salvatore ; Marmorino, Federica ; Lonardi, Sara ; Rimassa, Lorenza ; Sartore-Bianchi, Andrea ; Borelli, Beatrice ; Tampellini, Marco ; Bustreo, Sara ; Claravezza, Matteo ; Boccaccino, Alessandra ; Murialdo, Roberto ; Zaniboni, Alberto ; Tomasello, Gianluca ; Loupakis, Fotios ; Adamo, Vincenzo ; Tonini, Giuseppe ; Cortesi, Enrico ; de Braud, Filippo ; Cremolini, Chiara ; Pietrantonio, Filippo
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2020-08, Vol.123 (3), p.403-409
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Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-l...
Author / Creator:Sartore-Bianchi, Andrea, MD ; Trusolino, Livio, MD ; Martino, Cosimo, PhD ; Bencardino, Katia, MD ; Lonardi, Sara, MD ; Bergamo, Francesca, MD ; Zagonel, Vittorina, MD ; Leone, Francesco, MD ; Depetris, Ilaria, MD ; Martinelli, Erika, MD ; Troiani, Teresa, MD ; Ciardiello, Fortunato, Prof ; Racca, Patrizia, MD ; Bertotti, Andrea, MD ; Siravegna, Giulia, MSc ; Torri, Valter, MD ; Amatu, Alessio, MD ; Ghezzi, Silvia, MSc ; Marrapese, Giovanna, PhD ; Palmeri, Laura, MD ; Valtorta, Emanuele, PhD ; Cassingena, Andrea, MSc ; Lauricella, Calogero, PhD ; Vanzulli, Angelo, MD ; Regge, Daniele, MD ; Veronese, Silvio, MSc ; Comoglio, Paolo M, Prof ; Bardelli, Alberto, PhD ; Marsoni, Silvia, Dr ; Siena, Salvatore, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-06, Vol.17 (6), p.738-746
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Spotlight on New Hallmarks of Drug-Resistance towards Personalized Care for Epithelial Ovarian Cancer
Author / Creator:Frezzini, Simona ; Lonardi, Sara
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2024-04, Vol.13 (7), p.611
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Safety and Tolerability of c-MET Inhibitors in Cancer
Author / Creator:Puccini, Alberto ; Marín-Ramos, Nagore I. ; Bergamo, Francesca ; Schirripa, Marta ; Lonardi, Sara ; Lenz, Heinz-Josef ; Loupakis, Fotios ; Battaglin, Francesca
Publisher:Cham: Springer International Publishing
Journal title:Drug safety, 2019-02, Vol.42 (2), p.211-233
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Assessment of a HER2 scoring system for colorectal cancer: results from a validation study
Author / Creator:Valtorta, Emanuele ; Martino, Cosimo ; Sartore-Bianchi, Andrea ; Penaullt-Llorca, Frédérique ; Viale, Giuseppe ; Risio, Mauro ; Rugge, Massimo ; Grigioni, Walter ; Bencardino, Katia ; Lonardi, Sara ; Zagonel, Vittorina ; Leone, Francesco ; Noe, Johannes ; Ciardiello, Fortunato ; Pinto, Carmine ; Labianca, Roberto ; Mosconi, Stefania ; Graiff, Claudio ; Aprile, Giuseppe ; Frau, Barbara ; Garufi, Carlo ; Loupakis, Fotios ; Racca, Patrizia ; Tonini, Giuseppe ; Lauricella, Calogero ; Veronese, Silvio ; Truini, Mauro ; Siena, Salvatore ; Marsoni, Silvia ; Gambacorta, Marcello
Publisher:New York: Nature Publishing Group US
Journal title:Modern pathology, 2015-11, Vol.28 (11), p.1481-1491
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The heterogeneous clinical and pathological landscapes of metastatic Braf -mutated colorectal cancer
Author / Creator:Fanelli, Giuseppe Nicolò ; Dal Pozzo, Carlo Alberto ; Depetris, Ilaria ; Schirripa, Marta ; Brignola, Stefano ; Biason, Paola ; Balistreri, Mariangela ; Dal Santo, Luca ; Lonardi, Sara ; Munari, Giada ; Loupakis, Fotios ; Fassan, Matteo
Publisher:England: BioMed Central
Journal title:Cancer cell international, 2020-01, Vol.20 (1), p.30-30, Article 30
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AtezoTRIBE: a randomised phase II study of FOLFOXIRI plus bevacizumab alone or in combination with atezolizumab as initial therapy for patients with unresectable metastatic colorectal cancer
Author / Creator:Antoniotti, Carlotta ; Borelli, Beatrice ; Rossini, Daniele ; Pietrantonio, Filippo ; Morano, Federica ; Salvatore, Lisa ; Lonardi, Sara ; Marmorino, Federica ; Tamberi, Stefano ; Corallo, Salvatore ; Tortora, Giampaolo ; Bergamo, Francesca ; Brunella, Di Stefano ; Boccaccino, Alessandra ; Grassi, Elisa ; Racca, Patrizia ; Tamburini, Emiliano ; Aprile, Giuseppe ; Moretto, Roberto ; Boni, Luca ; Falcone, Alfredo ; Cremolini, Chiara
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2020-07, Vol.20 (1), p.683-9, Article 683
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The role of PNI to predict survival in advanced hepatocellular carcinoma treated with Sorafenib
Author / Creator:Caputo, Francesco ; Dadduzio, Vincenzo ; Tovoli, Francesco ; Bertolini, Giulia ; Cabibbo, Giuseppe ; Cerma, Krisida ; Vivaldi, Caterina ; Faloppi, Luca ; Rizzato, Mario Domenico ; Piscaglia, Fabio ; Celsa, Ciro ; Fornaro, Lorenzo ; Marisi, Giorgia ; Conti, Fabio ; Silvestris, Nicola ; Silletta, Marianna ; Lonardi, Sara ; Granito, Alessandro ; Stornello, Caterina ; Massa, Valentina ; Astara, Giorgio ; Delcuratolo, Sabina ; Cascinu, Stefano ; Scartozzi, Mario ; Casadei-Gardini, Andrea
Publisher:United States: Public Library of Science
Journal title:PloS one, 2020-05, Vol.15 (5), p.e0232449-e0232449
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TSC loss is a clonal event in eosinophilic solid and cystic renal cell carcinoma: a multiregional tumor sampling study
Author / Creator:Munari, Enrico ; Settanni, Giulio ; Caliò, Anna ; Segala, Diego ; Lonardi, Sara ; Sandrini, Silvia ; Vacca, Paola ; Tumino, Nicola ; Marconi, Marcella ; Brunelli, Matteo ; Gobbo, Stefano ; Netto, George J. ; Moretta, Lorenzo ; Zamboni, Giuseppe ; Martignoni, Guido
Publisher:New York: Nature Publishing Group US
Journal title:Modern pathology, 2022-03, Vol.35 (3), p.376-385
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Survival outcomes from atezolizumab plus bevacizumab versus Lenvatinib in Child Pugh B unresectable hepatocellular carcinoma patients
Author / Creator:Rimini, Margherita ; Persano, Mara ; Tada, Toshifumi ; Suda, Goki ; Shimose, Shigeo ; Kudo, Masatoshi ; Cheon, Jaekyung ; Finkelmeier, Fabian ; Lim, Ho Yeong ; Presa, José ; Salani, Francesca ; Lonardi, Sara ; Piscaglia, Fabio ; Kumada, Takashi ; Sakamoto, Naoya ; Iwamoto, Hideki ; Aoki, Tomoko ; Chon, Hong Jae ; Himmelsbach, Vera ; Schirripa, Marta ; Montes, Margarida ; Vivaldi, Caterina ; Soldà, Caterina ; Hiraoka, Atsushi ; Sho, Takuya ; Niizeki, Takashi ; Nishida, Naoshi ; Steup, Christoph ; Hirooka, Masashi ; Kariyama, Kazuya ; Tani, Joji ; Atsukawa, Masanori ; Takaguchi, Koichi ; Itobayashi, Ei ; Fukunishi, Shinya ; Tsuji, Kunihiko ; Ishikawa, Toru ; Tajiri, Kazuto ; Ochi, Hironori ; Yasuda, Satoshi ; Toyoda, Hidenori ; Ogawa, Chikara ; Nishimura, Takashi ; Hatanaka, Takeshi ; Kakizaki, Satoru ; Shimada, Noritomo ; Kawata, Kazuhito ; Tada, Fujimasa ; Ohama, Hideko ; Nouso, Kazuhiro ; Morishita, Asahiro ; Tsutsui, Akemi ; Nagano, Takuya ; Itokawa, Norio ; Okubo, Tomomi ; Arai, Taeang ; Imai, Michitaka ; Kosaka, Hisashi ; Naganuma, Atsushi ; Koizumi, Yohei ; Nakamura, Shinichiro ; Kaibori, Masaki ; Iijima, Hiroko ; Hiasa, Yoichi ; Burgio, Valentina ; Scartozzi, Mario ; Cascinu, Stefano ; Casadei-Gardini, Andrea
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Journal of cancer research and clinical oncology, 2023-08, Vol.149 (10), p.7565-7577
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Neoadjuvant and adjuvant pembrolizumab plus chemotherapy in locally advanced gastric or gastro-oesophageal cancer (KEYNOTE-585): an interim analysis of the multicentre, double-blind, randomised phase...
Author / Creator:Shitara, Kohei, MD ; Rha, Sun Young, Prof ; Wyrwicz, Lucjan S, Prof ; Oshima, Takashi, MD ; Karaseva, Nina, MD ; Osipov, Mikhail, MD ; Yasui, Hisateru, MD ; Yabusaki, Hiroshi, MD ; Afanasyev, Sergey, MD ; Park, Young-Kyu, MD ; Al-Batran, Salah-Eddin, MD ; Yoshikawa, Takaki, MD ; Yanez, Patricio, MD ; Di Bartolomeo, Maria, MD ; Lonardi, Sara, MD ; Tabernero, Josep, Prof ; Van Cutsem, Eric, Prof ; Janjigian, Yelena Y, MD ; Oh, Do-Youn, Prof ; Xu, Jianming, MD ; Fang, Xiao, PhD ; Shih, Chie-Schin, MD ; Bhagia, Pooja, MD ; Bang, Yung-Jue, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2024-02, Vol.25 (2), p.212-224
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Trastuzumab deruxtecan in patients with HER2-positive advanced colorectal cancer (DESTINY-CRC02): primary results from a multicentre, randomised, phase 2 trial
Author / Creator:Raghav, Kanwal, MD ; Siena, Salvatore, MD ; Takashima, Atsuo, MD ; Kato, Takeshi, MD ; Van den Eynde, Marc, MD ; Pietrantonio, Filippo, MD ; Komatsu, Yoshito, MD ; Kawakami, Hisato, MD ; Peeters, Marc, MD ; Andre, Thierry, MD ; Lonardi, Sara, MD ; Yamaguchi, Kensei, MD ; Tie, Jeanne, MD ; Castro, Cristina Gravalos, MD ; Hsu, Hung-Chih, MD ; Strickler, John H, MD ; Kim, Tae-You, MD ; Cha, Yongjun, MD ; Barrios, Daniel, MD ; Yan, Qi, PhD ; Kamio, Takahiro, MD ; Kobayashi, Kojiro, MSc ; Boran, Aislyn, PhD ; Koga, Makito, PhD ; Allard, John D, PhD ; Yoshino, Takayuki, MD PhD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2024-09, Vol.25 (9), p.1147-1162
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The KEYNOTE-811 trial of dual PD-1 and HER2 blockade in HER2-positive gastric cancer

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Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal Cancer

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Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study

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Upfront FOLFOXIRI plus bevacizumab and reintroduction after progression versus mFOLFOX6 plus bevacizumab followed by FOLFIRI plus bevacizumab in the treatment of patients with metastatic colorectal ca...

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Upfront FOLFOXIRI plus bevacizumab with or without atezolizumab in the treatment of patients with metastatic colorectal cancer (AtezoTRIBE): a multicentre, open-label, randomised, controlled, phase 2...

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Ramucirumab versus placebo in combination with second-line FOLFIRI in patients with metastatic colorectal carcinoma that progressed during or after first-line therapy with bevacizumab, oxaliplatin, an...

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FOLFOXIRI plus bevacizumab versus FOLFIRI plus bevacizumab as first-line treatment of patients with metastatic colorectal cancer: updated overall survival and molecular subgroup analyses of the open-l...

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Trastuzumab deruxtecan in patients in the USA and Europe with HER2-positive advanced gastric or gastroesophageal junction cancer with disease progression on or after a trastuzumab-containing regimen (...

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The Pan-Immune-Inflammation Value is a new prognostic biomarker in metastatic colorectal cancer: results from a pooled-analysis of the Valentino and TRIBE first-line trials

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Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-l...

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Spotlight on New Hallmarks of Drug-Resistance towards Personalized Care for Epithelial Ovarian Cancer

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Safety and Tolerability of c-MET Inhibitors in Cancer

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Assessment of a HER2 scoring system for colorectal cancer: results from a validation study

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The heterogeneous clinical and pathological landscapes of metastatic Braf -mutated colorectal cancer

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AtezoTRIBE: a randomised phase II study of FOLFOXIRI plus bevacizumab alone or in combination with atezolizumab as initial therapy for patients with unresectable metastatic colorectal cancer

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The role of PNI to predict survival in advanced hepatocellular carcinoma treated with Sorafenib

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TSC loss is a clonal event in eosinophilic solid and cystic renal cell carcinoma: a multiregional tumor sampling study

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Survival outcomes from atezolizumab plus bevacizumab versus Lenvatinib in Child Pugh B unresectable hepatocellular carcinoma patients

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Neoadjuvant and adjuvant pembrolizumab plus chemotherapy in locally advanced gastric or gastro-oesophageal cancer (KEYNOTE-585): an interim analysis of the multicentre, double-blind, randomised phase...

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Trastuzumab deruxtecan in patients with HER2-positive advanced colorectal cancer (DESTINY-CRC02): primary results from a multicentre, randomised, phase 2 trial

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