A33 ADAM10 in Huntington’s disease synaptic dysfunctions
A33 ADAM10 in Huntington’s disease synaptic dysfunctions
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London: BMJ Publishing Group Ltd
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English
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London: BMJ Publishing Group Ltd
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BackgroundA disintegrin and metalloproteinase 10 (ADAM10) is a constitutive alpha-secretase found at the excitatory synapse and implicated in the molecular structure and function of adult neuronal circuitries. Recently, we described that active ADAM10 increases at the synapse in Huntington’s Disease (HD) striatum and cortex and impairs both the pre...
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A33 ADAM10 in Huntington’s disease synaptic dysfunctions
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TN_cdi_proquest_journals_2724388734
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2724388734
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ISSN
0022-3050
E-ISSN
1468-330X
DOI
10.1136/jnnp-2022-ehdn.33