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Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted by...

Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted by...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2733784799

Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted by metastasis

About this item

Full title

Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted by metastasis

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2022-11

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

CD8+ T cell responses are critical for anti-tumor immunity. While extensively profiled in the tumor microenvironment (TME), recent studies in mice identified responses in lymph nodes (LN) as essential; however, the role of LN in human cancer patients remains unknown. We examined CD8+ T cells in human head and neck squamous cell carcinomas, regional...

Alternative Titles

Full title

Dynamic CD8+ T cell responses to cancer immunotherapy in human regional lymph nodes are disrupted by metastasis

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2733784799

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2733784799

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2022.11.08.513062