Small Interfering RNA to Reduce Lipoprotein(a) in Cardiovascular Disease
Small Interfering RNA to Reduce Lipoprotein(a) in Cardiovascular Disease
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Author / Creator
OCEAN(a)-DOSE Trial Investigators , O’Donoghue, Michelle L. , Rosenson, Robert S. , Gencer, Baris , López, J. Antonio G. , Lepor, Norman E. , Baum, Seth J. , Stout, Elmer , Gaudet, Daniel , Knusel, Beat , Kuder, Julia F. , Ran, Xinhui , Murphy, Sabina A. , Wang, Huei , Wu, You , Kassahun, Helina and Sabatine, Marc S.
Publisher
United States: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
United States: Massachusetts Medical Society
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Scope and Contents
Contents
Lipoprotein(a) is similar to LDL cholesterol but contains apolipoprotein(a). A trial tested the effects of an oligonucleotide drug targeting apo(a) mRNA on lipoprotein(a) concentrations in patients with CVD.
Alternative Titles
Full title
Small Interfering RNA to Reduce Lipoprotein(a) in Cardiovascular Disease
Authors, Artists and Contributors
Author / Creator
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2737142100
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2737142100
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2211023
