Exploring the intricacies and pitfalls of the ATN framework: An assessment across cohorts and thresh...
Exploring the intricacies and pitfalls of the ATN framework: An assessment across cohorts and thresholding methodologies
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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The amyloid/tau/neurodegeneration (ATN) framework has redefined Alzheimer's disease (AD) toward a primarily biological entity. While it has found wide application in AD research, it was so far typically applied to single cohort studies using distinct data-driven thresholding methods. This poses the question of how concordant thresholds obtained usi...
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Full title
Exploring the intricacies and pitfalls of the ATN framework: An assessment across cohorts and thresholding methodologies
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TN_cdi_proquest_journals_2748015824
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2748015824
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E-ISSN
2692-8205
DOI
10.1101/2022.12.06.519269
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https://www.proquest.com/docview/2748015824?pq-origsite=primo&accountid=13902
