Reimagining Gene-Environment Interaction Analysis for Human Complex Traits
Reimagining Gene-Environment Interaction Analysis for Human Complex Traits
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
In this study, we introduce PIGEON-a novel statistical framework for quantifying and estimating polygenic gene-environment interaction (GxE) using a variance component analytical approach. Based on PIGEON, we outline the main objectives in GxE studies, demonstrate the flaws in existing GxE approaches, and introduce an innovative estimation procedur...
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Full title
Reimagining Gene-Environment Interaction Analysis for Human Complex Traits
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TN_cdi_proquest_journals_2754187932
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2754187932
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E-ISSN
2692-8205
DOI
10.1101/2022.12.11.519973
How to access this item
https://www.proquest.com/docview/2754187932?pq-origsite=primo&accountid=13902
