Targeted gene deletion with SpCas9 and multiple guide RNAs in Arabidopsis thaliana: four are better...
Targeted gene deletion with SpCas9 and multiple guide RNAs in Arabidopsis thaliana: four are better than two
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Background. In plant genome editing, RNA-guided nucleases such as Cas9 from Streptococcus pyogenes (SpCas9) predominantly induce small insertions or deletions at target sites. This can be used for inactivation of protein-coding genes by frame shift mutations. However, in some cases, it may be advantageous to delete larger chromosomal segments. This...
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Targeted gene deletion with SpCas9 and multiple guide RNAs in Arabidopsis thaliana: four are better than two
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TN_cdi_proquest_journals_2763156512
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2763156512
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E-ISSN
2692-8205
DOI
10.1101/2023.01.10.523375
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https://www.proquest.com/docview/2763156512?pq-origsite=primo&accountid=13902