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Nucleoside Diphosphate Kinases 1 and 2 regulate a protective liver response to a high-fat diet

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Nucleoside Diphosphate Kinases 1 and 2 regulate a protective liver response to a high-fat diet

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2766570702

Nucleoside Diphosphate Kinases 1 and 2 regulate a protective liver response to a high-fat diet

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Cold Spring Harbor: Cold Spring Harbor Laboratory Press

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Contents

De novo lipogenesis (DNL), the process whereby cells synthesize fatty acids from acetyl-coenzyme A (acetyl-CoA), is deregulated in diverse pathologies, including cancer. Here we report that DNL is negatively regulated by Nucleoside Diphosphate Kinases 1 and 2 (NME1/2), housekeeping enzymes involved in nucleotide homeostasis that were recently disco...

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Nucleoside Diphosphate Kinases 1 and 2 regulate a protective liver response to a high-fat diet

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Record Identifier

TN_cdi_proquest_journals_2766570702

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2766570702

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2023.01.15.524116

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