IQGAP2 regulates blood-brain barrier immune dynamics
IQGAP2 regulates blood-brain barrier immune dynamics
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Author / Creator
Katdare, Ketaki A , Kjar, Andrew , O'Brown, Natasha M , Neal, Emma H , Sorets, Alexander G , Shostak, Alena , Romero-Fernandez, Wilber , Kwiatkowski, Alexander J , Mlouk, Kate , Kim, Hyosung , Cowell, Rebecca P , Schwensen, Katrina R , Horner, Kensley B , Wilson, John T , Schrag, Matthew S , Megason, Sean G and Lippmann, Ethan S
Publisher
United States: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
United States: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Brain endothelial cells (BECs) play an important role in maintaining central nervous system (CNS) homeostasis through blood-brain barrier (BBB) functions. BECs express low baseline levels of adhesion receptors, which limits entry of leukocytes. However, the molecular mediators governing this phenotype remain mostly unclear. Here, we explored how in...
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Full title
IQGAP2 regulates blood-brain barrier immune dynamics
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Record Identifier
TN_cdi_proquest_journals_2774349161
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2774349161
Other Identifiers
ISSN
2692-8205
E-ISSN
2692-8205
DOI
10.1101/2023.02.07.527394