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IQGAP2 regulates blood-brain barrier immune dynamics

IQGAP2 regulates blood-brain barrier immune dynamics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2774349161

IQGAP2 regulates blood-brain barrier immune dynamics

About this item

Full title

IQGAP2 regulates blood-brain barrier immune dynamics

Publisher

United States: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2024-04

Language

English

Formats

Publication information

Publisher

United States: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Brain endothelial cells (BECs) play an important role in maintaining central nervous system (CNS) homeostasis through blood-brain barrier (BBB) functions. BECs express low baseline levels of adhesion receptors, which limits entry of leukocytes. However, the molecular mediators governing this phenotype remain mostly unclear. Here, we explored how in...

Alternative Titles

Full title

IQGAP2 regulates blood-brain barrier immune dynamics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2774349161

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2774349161

Other Identifiers

ISSN

2692-8205

E-ISSN

2692-8205

DOI

10.1101/2023.02.07.527394