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Receptor⁻Receptor Interactions in Multiple 5-HT1A Heteroreceptor Complexes in Raphe-Hippocampal 5-HT Transmission and Their Relevance for Depression and Its Treatment
Author / Creator:Borroto-Escuela, Dasiel O ; Narváez, Manuel ; Ambrogini, Patrizia ; Ferraro, Luca ; Brito, Ismel ; Romero-Fernandez, Wilber ; Andrade-Talavera, Yuniesky ; Flores-Burgess, Antonio ; Millon, Carmelo ; Gago, Belen ; Narvaez, Jose Angel ; Odagaki, Yuji ; Palkovits, Miklos ; Diaz-Cabiale, Zaida ; Fuxe, Kjell
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2018-06, Vol.23 (6), p.1341
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Fatal iatrogenic cerebral β-amyloid-related arteritis in a woman treated with lecanemab for Alzheimer’s disease
Author / Creator:Solopova, Elena ; Romero-Fernandez, Wilber ; Harmsen, Hannah ; Ventura-Antunes, Lissa ; Wang, Emmeline ; Shostak, Alena ; Maldonado, Jose ; Donahue, Manus J. ; Schultz, Daniel ; Coyne, Thomas M. ; Charidimou, Andreas ; Schrag, Matthew
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-12, Vol.14 (1), p.8220-8, Article 8220
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Dual disruption of aldehyde dehydrogenases 1 and 3 promotes functional changes in the glutathione redox system and enhances chemosensitivity in nonsmall cell lung cancer
Author / Creator:Rebollido-Rios, Rocio ; Venton, Geoffroy ; Sánchez-Redondo, Sara ; Iglesias i Felip, Carmela ; Fournet, Guy ; González, Elena ; Romero Fernández, Wilber ; Borroto Escuela, Dasiel Oscar ; Di Stefano, Barbara ; Penarroche-Díaz, Reinier ; Martin, Guillaume ; Ceylan, Ismail ; Costello, Regis ; Perez-Alea, Mileidys
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2020-03, Vol.39 (13), p.2756-2771
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CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states
Author / Creator:Leng, Kun ; Rose, Indigo V. L. ; Kim, Hyosung ; Xia, Wenlong ; Romero-Fernandez, Wilber ; Rooney, Brendan ; Koontz, Mark ; Li, Emmy ; Ao, Yan ; Wang, Shinong ; Krawczyk, Mitchell ; TCW, Julia ; Goate, Alison ; Zhang, Ye ; Ullian, Erik M. ; Sofroniew, Michael V. ; Fancy, Stephen P. J. ; Schrag, Matthew S. ; Lippmann, Ethan S. ; Kampmann, Martin
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2022-11, Vol.25 (11), p.1528-1542
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The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components
Author / Creator:Borroto-Escuela, Dasiel O ; Brito, Ismel ; Romero-Fernandez, Wilber ; Di Palma, Michael ; Oflijan, Julia ; Skieterska, Kamila ; Duchou, Jolien ; Van Craenenbroeck, Kathleen ; Suárez-Boomgaard, Diana ; Rivera, Alicia ; Guidolin, Diego ; Agnati, Luigi F ; Fuxe, Kjell
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2014-05, Vol.15 (5), p.8570-8590
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Detection, visualization and quantification of protein complexes in human Alzheimer’s disease brains using proximity ligation assay
Author / Creator:Romero-Fernandez, Wilber ; Carvajal-Tapia, Cristian ; Prusky, Alex ; Katdare, Ketaki A. ; Wang, Emmeline ; Shostak, Alena ; Ventura-Antunes, Lissa ; Harmsen, Hannah J. ; Lippmann, Ethan S. ; Fuxe, Kjell ; MacGurn, Jason A. ; Borroto-Escuela, Dasiel O. ; Schrag, Matthew S.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-07, Vol.13 (1), p.11948-11948, Article 11948
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Acute Cocaine Enhances Dopamine D2R Recognition and Signaling and Counteracts D2R Internalization in Sigma1R-D2R Heteroreceptor Complexes
Author / Creator:Borroto-Escuela, Dasiel O. ; Narváez, Manuel ; Romero-Fernández, Wilber ; Pinton, Luca ; Wydra, Karolina ; Filip, Malgorzata ; Beggiato, Sarah ; Tanganelli, Sergio ; Ferraro, Luca ; Fuxe, Kjell
Publisher:New York: Springer US
Journal title:Molecular neurobiology, 2019-10, Vol.56 (10), p.7045-7055
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A2AR Transmembrane 2 Peptide Administration Disrupts the A2AR-A2AR Homoreceptor but Not the A2AR-D2R Heteroreceptor Complex: Lack of Actions on Rodent Cocaine Self-Administration
Author / Creator:Borroto-Escuela, Dasiel O ; Wydra, Karolina ; Romero-Fernandez, Wilber ; Zhou, Zilong ; Frankowska, Malgorzata ; Filip, Malgorzata ; Fuxe, Kjell
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2019-12, Vol.20 (23), p.6100
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Combined treatment with Sigma1R and A2AR agonists fails to inhibit cocaine self-administration despite causing strong antagonistic accumbal A2AR-D2R complex interactions: the potential role of astrocy...
Author / Creator:Borroto-Escuela, Dasiel O ; Lopez-Salas, Alexander ; Wydra, Karolina ; Bartolini, Marco ; Zhou, Zilong ; Frankowska, Malgorzata ; Suder, Agata ; Benitez-Porres, Javier ; Romero-Fernandez, Wilber ; Filip, Malgorzata ; Fuxe, Kjell
Publisher:Switzerland: Frontiers Research Foundation
Journal title:Frontiers in molecular neuroscience, 2023-05, Vol.16, p.1106765-1106765
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Moonlighting Proteins and Protein–Protein Interactions as Neurotherapeutic Targets in the G Protein-Coupled Receptor Field
Author / Creator:Fuxe, Kjell ; Borroto-Escuela, Dasiel O ; Romero-Fernandez, Wilber ; Palkovits, Miklós ; Tarakanov, Alexander O ; Ciruela, Francisco ; Agnati, Luigi F
Journal title:Neuropsychopharmacology (New York, N.Y.), 2014, Vol.39 (1), p.131-155
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Phospholipase D3 (PLD3) Regulates Lysosomal Biogenesis
Author / Creator:Wang, Yongchao ; Fernandez, Wilber Romero ; Carvajal‐Tapia, Cristian O ; Shostak, Alena ; Rieschick, Paige ; Appelbaum, Nathan ; Schrag, Matthew
Publisher:Hoboken: John Wiley and Sons Inc
Journal title:Alzheimer's & dementia, 2024-12, Vol.20 (S1), p.n/a
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Basic Science and Pathogenesis
Author / Creator:Wang, Yongchao ; Fernandez, Wilber Romero ; Carvajal-Tapia, Cristian O ; Shostak, Alena ; Rieschick, Paige ; Appelbaum, Nathan ; Schrag, Matthew
Publisher:United States
Journal title:Alzheimer's & dementia, 2024-12, Vol.20 Suppl 1, p.e087739
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Moonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field
Author / Creator:Fuxe, Kjell ; Borroto-Escuela, Dasiel O ; Romero-Fernandez, Wilber ; Palkovits, Miklós ; Tarakanov, Alexander O ; Ciruela, Francisco ; Agnati, Luigi F
Publisher:England: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2014-01, Vol.39 (1), p.131-155
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The mGlu5 Receptor Protomer-Mediated Dopamine D2 Receptor Trans-Inhibition Is Dependent on the Adenosine A2A Receptor Protomer: Implications for Parkinson’s Disease
Author / Creator:Romero-Fernandez, Wilber ; Taura, Jaume J. ; Crans, René A. J. ; Lopez-Cano, Marc ; Fores-Pons, Ramon ; Narváez, Manuel ; Carlsson, Jens ; Ciruela, Francisco ; Fuxe, Kjell ; Borroto-Escuela, Dasiel O.
Publisher:New York: Springer US
Journal title:Molecular neurobiology, 2022-10, Vol.59 (10), p.5955-5969
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The mGlu 5 Receptor Protomer-Mediated Dopamine D 2 Receptor Trans-Inhibition Is Dependent on the Adenosine A 2A Receptor Protomer: Implications for Parkinson's Disease
Author / Creator:Romero-Fernandez, Wilber ; Taura, Jaume J. ; Crans, Rene A. J. ; Lopez-Cano, Marc ; Fores-Pons, Ramon ; Narvaez, Manuel ; Carlsson, Jens ; Ciruela, Francisco ; Fuxe, Kjell ; Borroto-Escuela, Dasiel O.
Journal title:Molecular neurobiology, 2022, Vol.59 (10), p.5955
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Conventional culture media enriched with extracts of quinoa, amaranth and chia promotes the Staphylococcus aureus growth
Author / Creator:Elizabeth Proaño-Pérez ; Israel Manjarres-Raza ; Cristian Carvajal-Tapia ; Wilber Romero-Fernandez
Publisher:Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales
Journal title:Kasmera, 2017-08, Vol.45 (1), p.8-15
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Medio de cultivo convencional enriquecido con extractos de quinoa, amaranto y chía promueve el crecimiento de Staphylococcus aureus
Author / Creator:Proaño-Pérez Elizabeth ; Manjarres-Raza Israel ; Carvajal-Tapia Cristian ; Romero-Fernandez Wilber
Publisher:Universidad del Zulia,Facultad de Medicina,Departamento de Enfermedades Infecciosas y Tropicales
Journal title:Kasmera, 2017-06, Vol.45 (1), p.8-15
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On the G-Protein-Coupled Receptor Heteromers and Their Allosteric Receptor-Receptor Interactions in the Central Nervous System : Focus on Their Role in Pain Modulation
Author / Creator:Borroto-Escuela, Dasiel O. ; Romero-Fernandez, Wilber ; Rivera, Alicia ; Van Craenenbroeck, Kathleen ; Tarakanov, Alexander O. ; Agnati, Luigi F. ; Fuxe, Kjell
Publisher:Cairo, Egypt: Hindawi Puplishing Corporation
Journal title:Evidence-based complementary and alternative medicine, 2013-01, Vol.2013 (2013), p.1-17
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Moonlighting Proteins and Protein―Protein Interactions as Neurotherapeutic Targets in the G Protein-Coupled Receptor Field
Author / Creator:FUXE, Kjell ; BORROTO-ESCUELA, Dasiel O ; ROMERO-FERNANDEZ, Wilber ; PALKOVITS, Miklós ; TARAKANOV, Alexander O ; CIRUELA, Francisco ; AGNATI, Luigi F
Publisher:Basingstoke: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2014, Vol.39 (1), p.131-155
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Evidencias biofisicas de la formación del heteromero entre el receptor de oxitocina y el receptor de serotonina 1A
Author / Creator:Perez-Betancourt, Yunys ; Manjarres-Raza, Israel ; Carvajal-Tapia, Cristian ; Tayo-Montenegro, Andres ; Garcia-Barcelo, Maria ; Romero-Fernandez, Wilber
Publisher:Universidad del Zulia
Journal title:Investigación clínica, 2017-12, Vol.58 (4), p.352
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Receptor⁻Receptor Interactions in Multiple 5-HT1A Heteroreceptor Complexes in Raphe-Hippocampal 5-HT Transmission and Their Relevance for Depression and Its Treatment

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Fatal iatrogenic cerebral β-amyloid-related arteritis in a woman treated with lecanemab for Alzheimer’s disease

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Dual disruption of aldehyde dehydrogenases 1 and 3 promotes functional changes in the glutathione redox system and enhances chemosensitivity in nonsmall cell lung cancer

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CRISPRi screens in human iPSC-derived astrocytes elucidate regulators of distinct inflammatory reactive states

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The G protein-coupled receptor heterodimer network (GPCR-HetNet) and its hub components

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Detection, visualization and quantification of protein complexes in human Alzheimer’s disease brains using proximity ligation assay

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Acute Cocaine Enhances Dopamine D2R Recognition and Signaling and Counteracts D2R Internalization in Sigma1R-D2R Heteroreceptor Complexes

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A2AR Transmembrane 2 Peptide Administration Disrupts the A2AR-A2AR Homoreceptor but Not the A2AR-D2R Heteroreceptor Complex: Lack of Actions on Rodent Cocaine Self-Administration

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Combined treatment with Sigma1R and A2AR agonists fails to inhibit cocaine self-administration despite causing strong antagonistic accumbal A2AR-D2R complex interactions: the potential role of astrocy...

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Moonlighting Proteins and Protein–Protein Interactions as Neurotherapeutic Targets in the G Protein-Coupled Receptor Field

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Phospholipase D3 (PLD3) Regulates Lysosomal Biogenesis

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Basic Science and Pathogenesis

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Moonlighting proteins and protein-protein interactions as neurotherapeutic targets in the G protein-coupled receptor field

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The mGlu5 Receptor Protomer-Mediated Dopamine D2 Receptor Trans-Inhibition Is Dependent on the Adenosine A2A Receptor Protomer: Implications for Parkinson’s Disease

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The mGlu 5 Receptor Protomer-Mediated Dopamine D 2 Receptor Trans-Inhibition Is Dependent on the Adenosine A 2A Receptor Protomer: Implications for Parkinson's Disease

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Conventional culture media enriched with extracts of quinoa, amaranth and chia promotes the Staphylococcus aureus growth

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Medio de cultivo convencional enriquecido con extractos de quinoa, amaranto y chía promueve el crecimiento de Staphylococcus aureus

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On the G-Protein-Coupled Receptor Heteromers and Their Allosteric Receptor-Receptor Interactions in the Central Nervous System : Focus on Their Role in Pain Modulation

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Moonlighting Proteins and Protein―Protein Interactions as Neurotherapeutic Targets in the G Protein-Coupled Receptor Field

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Evidencias biofisicas de la formación del heteromero entre el receptor de oxitocina y el receptor de serotonina 1A

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