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A multi-omics genome-and-transcriptome single-cell atlas of human preimplantation embryogenesis reve...

A multi-omics genome-and-transcriptome single-cell atlas of human preimplantation embryogenesis reve...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2785473931

A multi-omics genome-and-transcriptome single-cell atlas of human preimplantation embryogenesis reveals the cellular and molecular impact of chromosome instability

About this item

Full title

A multi-omics genome-and-transcriptome single-cell atlas of human preimplantation embryogenesis reveals the cellular and molecular impact of chromosome instability

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2023-03

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The frequent acquisition of genomic abnormalities in human preimplantation embryos is a leading cause of pregnancy loss, but does not necessarily prohibit healthy offspring. However, the impact of genomic abnormalities on cellular states and development of the early human embryo remains largely unclear. Here, we characterise aneuploidy and reconstr...

Alternative Titles

Full title

A multi-omics genome-and-transcriptome single-cell atlas of human preimplantation embryogenesis reveals the cellular and molecular impact of chromosome instability

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2785473931

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2785473931

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2023.03.08.530586