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Silence of resident microglia in GPI anchorless prion disease and activation of microglia in Gerstma...

Silence of resident microglia in GPI anchorless prion disease and activation of microglia in Gerstma...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2823853529

Silence of resident microglia in GPI anchorless prion disease and activation of microglia in Gerstmann-Sträussler-Scheinker disease and sporadic Creutzfeldt-Jakob disease

About this item

Full title

Silence of resident microglia in GPI anchorless prion disease and activation of microglia in Gerstmann-Sträussler-Scheinker disease and sporadic Creutzfeldt-Jakob disease

Publisher

England: Oxford University Press

Journal title

Journal of neuropathology and experimental neurology, 2022-12, Vol.82 (1), p.38-48

Language

English

Formats

Publication information

Publisher

England: Oxford University Press

More information

Scope and Contents

Contents

Abstract
GPI anchorless prion diseases (GPIALPs) show numerous coarse prion protein (PrP) deposits in the CNS but neuropil spongiform changes are mild and the incidence of dementia is low. Here, we examined differences in resident microglial phenotypes between GPIALP (D178fs25) and the other prion diseases Gerstmann-Sträussler-Scheinker (GSS) di...

Alternative Titles

Full title

Silence of resident microglia in GPI anchorless prion disease and activation of microglia in Gerstmann-Sträussler-Scheinker disease and sporadic Creutzfeldt-Jakob disease

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2823853529

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2823853529

Other Identifiers

ISSN

0022-3069

E-ISSN

1554-6578

DOI

10.1093/jnen/nlac098

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