810 Novel renal cell carcinoma immunotherapy combining TLR9-targeted STAT3 antisense oligonucleotide...
810 Novel renal cell carcinoma immunotherapy combining TLR9-targeted STAT3 antisense oligonucleotide with PD-1 blockade
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London: BMJ Publishing Group LTD
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English
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London: BMJ Publishing Group LTD
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BackgroundNovel therapy combinations utilizing PD-1 immune checkpoint inhibition have improved outcomes in patients with RCC; however, positive clinical responses are limited to select individuals.1 Various studies indicate resistance is mediated partly through STAT3 induced activity and a concomitant accumulation of tumor infiltrating myeloid deri...
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810 Novel renal cell carcinoma immunotherapy combining TLR9-targeted STAT3 antisense oligonucleotide with PD-1 blockade
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TN_cdi_proquest_journals_2840708176
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2840708176
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E-ISSN
2051-1426
DOI
10.1136/jitc-2022-SITC2022.0810