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810 Novel renal cell carcinoma immunotherapy combining TLR9-targeted STAT3 antisense oligonucleotide...

810 Novel renal cell carcinoma immunotherapy combining TLR9-targeted STAT3 antisense oligonucleotide...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2840708176

810 Novel renal cell carcinoma immunotherapy combining TLR9-targeted STAT3 antisense oligonucleotide with PD-1 blockade

About this item

Full title

810 Novel renal cell carcinoma immunotherapy combining TLR9-targeted STAT3 antisense oligonucleotide with PD-1 blockade

Publisher

London: BMJ Publishing Group LTD

Journal title

Journal for immunotherapy of cancer, 2022, Vol.10 (Suppl 2), p.A846-A846

Language

English

Publication information

Publisher

London: BMJ Publishing Group LTD

More information

Scope and Contents

Contents

BackgroundNovel therapy combinations utilizing PD-1 immune checkpoint inhibition have improved outcomes in patients with RCC; however, positive clinical responses are limited to select individuals.1 Various studies indicate resistance is mediated partly through STAT3 induced activity and a concomitant accumulation of tumor infiltrating myeloid deri...

Alternative Titles

Full title

810 Novel renal cell carcinoma immunotherapy combining TLR9-targeted STAT3 antisense oligonucleotide with PD-1 blockade

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2840708176

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2840708176

Other Identifiers

E-ISSN

2051-1426

DOI

10.1136/jitc-2022-SITC2022.0810

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