A G-quadruplex-binding platinum complex induces cancer mitochondrial dysfunction in vitro and in viv...
A G-quadruplex-binding platinum complex induces cancer mitochondrial dysfunction in vitro and in vivo independently of ROS induction
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Washington: American Chemical Society
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Language
English
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Washington: American Chemical Society
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G-quadruplex DNA (G4) is a non-canonical structure forming in guanine-rich regions, which play a vital role in cancer biology and are now being acknowledged in both nuclear and mitochondrial (mt) genome. However, the impact of G4-based targeted therapy on both nuclear and mt genome, affecting mt function and its underlying mechanisms remain largely...
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Full title
A G-quadruplex-binding platinum complex induces cancer mitochondrial dysfunction in vitro and in vivo independently of ROS induction
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TN_cdi_proquest_journals_2890486914
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2890486914
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E-ISSN
2573-2293
DOI
10.26434/chemrxiv-2023-npl8r
