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Cardiac Molecular Analysis Reveals Aging-Associated Metabolic Alterations Promoting Glycosaminoglyca...

Cardiac Molecular Analysis Reveals Aging-Associated Metabolic Alterations Promoting Glycosaminoglyca...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2891353750

Cardiac Molecular Analysis Reveals Aging-Associated Metabolic Alterations Promoting Glycosaminoglycans Accumulation Via Hexosamine Biosynthetic Pathway

About this item

Full title

Cardiac Molecular Analysis Reveals Aging-Associated Metabolic Alterations Promoting Glycosaminoglycans Accumulation Via Hexosamine Biosynthetic Pathway

Publisher

United States: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2023-11

Language

English

Formats

Publication information

Publisher

United States: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Age is a prominent risk factor for cardiometabolic disease, and often leads to heart structural and functional changes. However, precise molecular mechanisms underlying cardiac remodeling and dysfunction resulting from physiological aging per se remain elusive. Understanding these mechanisms requires biological models with optimal translation to hu...

Alternative Titles

Full title

Cardiac Molecular Analysis Reveals Aging-Associated Metabolic Alterations Promoting Glycosaminoglycans Accumulation Via Hexosamine Biosynthetic Pathway

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2891353750

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2891353750

Other Identifiers

ISSN

2692-8205

E-ISSN

2692-8205

DOI

10.1101/2023.11.17.567640