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Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transform...

Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transform...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2895911206

Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival

About this item

Full title

Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival

Publisher

United States: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2023-12

Language

English

Formats

Publication information

Publisher

United States: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Under chronic stress, cells must balance competing demands between cellular survival and tissue function. In metabolic dysfunction-associated steatotic liver disease (MASLD, formerly NAFLD/NASH), hepatocytes cooperate with structural and immune cells to perform crucial metabolic, synthetic, and detoxification functions despite nutrient imbalances....

Alternative Titles

Full title

Chronic metabolic stress drives developmental programs and loss of tissue functions in non-transformed liver that mirror tumor states and stratify survival

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2895911206

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2895911206

Other Identifiers

ISSN

2692-8205

E-ISSN

2692-8205

DOI

10.1101/2023.11.30.569407