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51 results for Yilmaz,+Ömer+H

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ArticlesPeer ReviewedFull Text
mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake
Author / Creator:Yilmaz, Ömer H. ; Katajisto, Pekka ; Lamming, Dudley W. ; Gültekin, Yetis ; Bauer-Rowe, Khristian E. ; Sengupta, Shomit ; Birsoy, Kivanc ; Dursun, Abdulmetin ; Yilmaz, V. Onur ; Selig, Martin ; Nielsen, G. Petur ; Mino-Kenudson, Mari ; Zukerberg, Lawrence R. ; Bhan, Atul K. ; Deshpande, Vikram ; Sabatini, David M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-06, Vol.486 (7404), p.490-495
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SOX17 enables immune evasion of early colorectal adenomas and cancers
Author / Creator:Goto, Norihiro ; Westcott, Peter M. K. ; Goto, Saori ; Imada, Shinya ; Taylor, Martin S. ; Eng, George ; Braverman, Jonathan ; Deshpande, Vikram ; Jacks, Tyler ; Agudo, Judith ; Yilmaz, Ömer H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2024-03, Vol.627 (8004), p.636-645
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A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma
Author / Creator:Tammela, Tuomas ; Sanchez-Rivera, Francisco J. ; Cetinbas, Naniye Malli ; Wu, Katherine ; Joshi, Nikhil S. ; Helenius, Katja ; Park, Yoona ; Azimi, Roxana ; Kerper, Natanya R. ; Wesselhoeft, R. Alexander ; Gu, Xin ; Schmidt, Leah ; Cornwall-Brady, Milton ; Yilmaz, Ömer H. ; Xue, Wen ; Katajisto, Pekka ; Bhutkar, Arjun ; Jacks, Tyler
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-05, Vol.545 (7654), p.355-359
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Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium
Author / Creator:Pentinmikko, Nalle ; Iqbal, Sharif ; Mana, Miyeko ; Andersson, Simon ; Cognetta, Armand B. ; Suciu, Radu M. ; Roper, Jatin ; Luopajärvi, Kalle ; Markelin, Eino ; Gopalakrishnan, Swetha ; Smolander, Olli-Pekka ; Naranjo, Santiago ; Saarinen, Tuure ; Juuti, Anne ; Pietiläinen, Kirsi ; Auvinen, Petri ; Ristimäki, Ari ; Gupta, Nitin ; Tammela, Tuomas ; Jacks, Tyler ; Sabatini, David M. ; Cravatt, Benjamin F. ; Yilmaz, Ömer H. ; Katajisto, Pekka
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-07, Vol.571 (7765), p.398-402
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Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells
Author / Creator:Yilmaz, Ömer H. ; Valdez, Riccardo ; Theisen, Brian K. ; Guo, Wei ; Ferguson, David O. ; Wu, Hong ; Morrison, Sean J.
Publisher:London: Nature Publishing
Journal title:Nature, 2006-05, Vol.441 (7092), p.475-482
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Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes
Author / Creator:Genshaft, Alex S ; Ziegler, Carly G. K. ; Tzouanas, Constantine N. ; Mead, Benjamin E. ; Jaeger, Alex M. ; Navia, Andrew W. ; King, Ryan P. ; Mana, Miyeko D. ; Huang, Siyi ; Mitsialis, Vanessa ; Snapper, Scott B. ; Yilmaz, Ömer H. ; Jacks, Tyler ; Van Humbeck, Jeffrey F. ; Shalek, Alex K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-08, Vol.12 (1), p.4995-4995, Article 4995
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CRAD as a cytoskeletal tumour suppressor
Author / Creator:Eng, George ; Braverman, Jonathan ; Yilmaz, Ömer H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2018-11, Vol.20 (11), p.1232-1233
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Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints
Author / Creator:Kong, Yi Wen ; Dreaden, Erik C. ; Morandell, Sandra ; Zhou, Wen ; Dhara, Sanjeev S. ; Sriram, Ganapathy ; Lam, Fred C. ; Patterson, Jesse C. ; Quadir, Mohiuddin ; Dinh, Anh ; Shopsowitz, Kevin E. ; Varmeh, Shohreh ; Yilmaz, Ömer H. ; Lippard, Stephen J. ; Reinhardt, H. Christian ; Hemann, Michael T. ; Hammond, Paula T. ; Yaffe, Michael B.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-08, Vol.11 (1), p.4124-4124, Article 4124
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High‐fat diet in a mouse insulin‐resistant model induces widespread rewiring of the phosphotyrosine signaling network
Author / Creator:Dittmann, Antje ; Kennedy, Norman J ; Soltero, Nina L ; Morshed, Nader ; Mana, Miyeko D ; Yilmaz, Ömer H ; Davis, Roger J ; White, Forest M
Publisher:London: Nature Publishing Group UK
Journal title:Molecular systems biology, 2019-08, Vol.15 (8), p.e8849-n/a
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ArticlesPeer ReviewedFull Text
Dietary Regulation of Adult Stem Cells
Author / Creator:Mana, Miyeko D. ; Kuo, Elaine Yih-Shuen ; Yilmaz, Ömer H.
Publisher:Cham: Springer International Publishing
Journal title:Current stem cell reports, 2017-03, Vol.3 (1), p.1-8
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ArticlesPeer ReviewedFull Text
Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation
Author / Creator:Mead, Benjamin E. ; Hattori, Kazuki ; Levy, Lauren ; Imada, Shinya ; Goto, Norihiro ; Vukovic, Marko ; Sze, Daphne ; Kummerlowe, Conner ; Matute, Juan D. ; Duan, Jinzhi ; Langer, Robert ; Blumberg, Richard S. ; Ordovas-Montanes, Jose ; Yilmaz, Ömer H. ; Karp, Jeffrey M. ; Shalek, Alex K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature biomedical engineering, 2022-04, Vol.6 (4), p.476-494
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ArticlesPeer ReviewedFull Text
Publisher Correction: Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes
Author / Creator:Genshaft, Alex S. ; Ziegler, Carly G. K. ; Tzouanas, Constantine N. ; Mead, Benjamin E. ; Jaeger, Alex M. ; Navia, Andrew W. ; King, Ryan P. ; Mana, Miyeko D. ; Huang, Siyi ; Mitsialis, Vanessa ; Snapper, Scott B. ; Yilmaz, Ömer H. ; Jacks, Tyler ; Van Humbeck, Jeffrey F. ; Shalek, Alex K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-09, Vol.12 (1), p.5361-5361, Article 5361
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ArticlesPeer ReviewedFull Text
Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer
Author / Creator:Schmidt, Daniel R. ; Gramatikov, Iva Monique T. ; Sheen, Allison ; Williams, Christopher L. ; Hurwitz, Martina ; Dodge, Laura E. ; Holupka, Edward ; Kiger, W. S. ; Cornwall-Brady, Milton R. ; Huang, Wei ; Mak, Howard H. ; Cormier, Kathleen S ; Condon, Charlene ; Dane Wittrup, K. ; Yilmaz, Ömer H. ; Stevenson, Mary Ann ; Down, Julian D. ; Floyd, Scott R. ; Roper, Jatin ; Vander Heiden, Matthew G.
Publisher:London: Nature Publishing Group UK
Journal title:Communications medicine, 2023-08, Vol.3 (1), p.108-20, Article 108
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High-fat diet enhances stemness and tumorigenicity of intestinal progenitors
Author / Creator:Beyaz, Semir ; Mana, Miyeko D. ; Roper, Jatin ; Kedrin, Dmitriy ; Saadatpour, Assieh ; Hong, Sue-Jean ; Bauer-Rowe, Khristian E. ; Xifaras, Michael E. ; Akkad, Adam ; Arias, Erika ; Pinello, Luca ; Katz, Yarden ; Shinagare, Shweta ; Abu-Remaileh, Monther ; Mihaylova, Maria M. ; Lamming, Dudley W. ; Dogum, Rizkullah ; Guo, Guoji ; Bell, George W. ; Selig, Martin ; Nielsen, G. Petur ; Gupta, Nitin ; Ferrone, Cristina R. ; Deshpande, Vikram ; Yuan, Guo-Cheng ; Orkin, Stuart H. ; Sabatini, David M. ; Yilmaz, Ömer H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-03, Vol.531 (7592), p.53-58
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Colonoscopy-based colorectal cancer modeling in mice with CRISPR–Cas9 genome editing and organoid transplantation
Author / Creator:Roper, Jatin ; Tammela, Tuomas ; Akkad, Adam ; Almeqdadi, Mohammad ; Santos, Sebastian B ; Jacks, Tyler ; Yilmaz, Ömer H
Publisher:London: Nature Publishing Group UK
Journal title:Nature protocols, 2018-02, Vol.13 (2), p.217-234
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Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis
Author / Creator:Lannagan, Tamsin R M ; Lee, Young K ; Wang, Tongtong ; Roper, Jatin ; Bettington, Mark L ; Fennell, Lochlan ; Vrbanac, Laura ; Jonavicius, Lisa ; Somashekar, Roshini ; Gieniec, Krystyna ; Yang, Miao ; Ng, Jia Q ; Suzuki, Nobumi ; Ichinose, Mari ; Wright, Josephine A ; Kobayashi, Hiroki ; Putoczki, Tracey L ; Hayakawa, Yoku ; Leedham, Simon J ; Abud, Helen E ; Yilmaz, Ömer H ; Marker, Julie ; Klebe, Sonja ; Wirapati, Pratyaksha ; Mukherjee, Siddhartha ; Tejpar, Sabine ; Leggett, Barbara A ; Whitehall, Vicki L J ; Worthley, Daniel L ; Woods, Susan L
Publisher:England: BMJ Publishing Group LTD
Journal title:Gut, 2019-04, Vol.68 (4), p.684-692
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Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense
Author / Creator:Lassen, Kara G. ; Kuballa, Petric ; Conway, Kara L. ; Patel, Khushbu K. ; Becker, Christine E. ; Peloquin, Joanna M. ; Villablanca, Eduardo J. ; Norman, Jason M. ; Liu, Ta-Chiang ; Heath, Robert J. ; Becker, Morgan L. ; Fagbami, Lola ; Horn, Heiko ; Mercer, Johnathan ; Yilmaz, Omer H. ; Jaffe, Jacob D. ; Shamji, Alykhan F. ; Bhan, Atul K. ; Carr, Steven A. ; Daly, Mark J. ; Virgin, Herbert W. ; Schreiber, Stuart L. ; Stappenbeck, Thaddeus S. ; Xavier, Ramnik J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-05, Vol.111 (21), p.7741-7746
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MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors
Author / Creator:Birsoy, Kivanç ; Wang, Tim ; Possemato, Richard ; Yilmaz, Omer H ; Koch, Catherine E ; Chen, Walter W ; Hutchins, Amanda W ; Gultekin, Yetis ; Peterson, Tim R ; Carette, Jan E ; Brummelkamp, Thijn R ; Clish, Clary B ; Sabatini, David M
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2013-01, Vol.45 (1), p.104-108
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Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan
Author / Creator:Lamming, Dudley W. ; Mihaylova, Maria M. ; Katajisto, Pekka ; Baar, Emma L. ; Yilmaz, Omer H. ; Hutchins, Amanda ; Gultekin, Yetis ; Gaither, Rachel ; Sabatini, David M.
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2014-10, Vol.13 (5), p.911-917
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The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells
Author / Creator:Beyaz, Semir ; Kim, Ji Hyung ; Pinello, Luca ; Xifaras, Michael E ; Hu, Yu ; Huang, Jialiang ; Kerenyi, Marc A ; Das, Partha P ; Barnitz, R Anthony ; Herault, Aurelie ; Dogum, Rizkullah ; Haining, W Nicholas ; Yilmaz, Ömer H ; Passegue, Emmanuelle ; Yuan, Guo-Cheng ; Orkin, Stuart H ; Winau, Florian
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2017-02, Vol.18 (2), p.184-195
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mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake

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SOX17 enables immune evasion of early colorectal adenomas and cancers

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A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma

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Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium

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Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

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Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes

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CRAD as a cytoskeletal tumour suppressor

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Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints

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High‐fat diet in a mouse insulin‐resistant model induces widespread rewiring of the phosphotyrosine signaling network

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Dietary Regulation of Adult Stem Cells

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Screening for modulators of the cellular composition of gut epithelia via organoid models of intestinal stem cell differentiation

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Publisher Correction: Live cell tagging tracking and isolation for spatial transcriptomics using photoactivatable cell dyes

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Ablative radiotherapy improves survival but does not cure autochthonous mouse models of prostate and colorectal cancer

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High-fat diet enhances stemness and tumorigenicity of intestinal progenitors

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Colonoscopy-based colorectal cancer modeling in mice with CRISPR–Cas9 genome editing and organoid transplantation

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Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis

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Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense

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MCT1-mediated transport of a toxic molecule is an effective strategy for targeting glycolytic tumors

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Depletion of Rictor, an essential protein component of mTORC2, decreases male lifespan

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The histone demethylase UTX regulates the lineage-specific epigenetic program of invariant natural killer T cells

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