Disease progression modelling reveals heterogeneity in trajectories of Lewy-type alpha-synuclein pat...
Disease progression modelling reveals heterogeneity in trajectories of Lewy-type alpha-synuclein pathology
About this item
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Author / Creator
Mastenbroek, Sophie E , Vogel, Jacob W , Collij, Lyduine E , Serrano, Geidy E , Tremblay, Cecilia , Young, Alexandra L , Arce, Richard A , Shill, Holly A , Driver-Dunckley, Erika D , Mehta, Shyamal H , Belden, Christine M , Atri, Alireza , Choudhury, Parichita , Barkhof, Frederik , Adler, Charles H , Ossenkoppele, Rik , Beach, Thomas G and Hansson, Oskar
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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More information
Scope and Contents
Contents
Lewy body (LB) disorders, characterized by the aggregation of misfolded alpha-synuclein proteins, exhibit notable clinical heterogeneity. This may be due to variations in accumulation patterns of LB neuropathology. By applying data-driven disease progression modelling to regional neuropathological LB density scores from 814 brain donors, we describ...
Alternative Titles
Full title
Disease progression modelling reveals heterogeneity in trajectories of Lewy-type alpha-synuclein pathology
Authors, Artists and Contributors
Author / Creator
Vogel, Jacob W
Collij, Lyduine E
Serrano, Geidy E
Tremblay, Cecilia
Young, Alexandra L
Arce, Richard A
Shill, Holly A
Driver-Dunckley, Erika D
Mehta, Shyamal H
Belden, Christine M
Atri, Alireza
Choudhury, Parichita
Barkhof, Frederik
Adler, Charles H
Ossenkoppele, Rik
Beach, Thomas G
Hansson, Oskar
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2899154180
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2899154180
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2023.12.05.569878
How to access this item
https://www.proquest.com/docview/2899154180?pq-origsite=primo&accountid=13902
