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Bispecific PSMA-617 / RM2 Heterodimer for Theranostics Applications in Prostate Cancer

Bispecific PSMA-617 / RM2 Heterodimer for Theranostics Applications in Prostate Cancer

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2913189927

Bispecific PSMA-617 / RM2 Heterodimer for Theranostics Applications in Prostate Cancer

About this item

Full title

Bispecific PSMA-617 / RM2 Heterodimer for Theranostics Applications in Prostate Cancer

Publisher

Washington: American Chemical Society

Journal title

ChemRxiv, 2024-01

Language

English

Formats

Publication information

Publisher

Washington: American Chemical Society

More information

Scope and Contents

Contents

PSMA and GRPR protein receptors are upregulated during prostate cancer (PCa) progression, and thus they have both been used for diagnostic molecular imaging and therapy of the disease. To address tumor heterogeneity, we synthesized and evaluated the bispecific PSMA/GRPR ligand (3) with a 10 atom spacer between PSMA-617 (1) and the GRPR antagonist R...

Alternative Titles

Full title

Bispecific PSMA-617 / RM2 Heterodimer for Theranostics Applications in Prostate Cancer

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2913189927

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2913189927

Other Identifiers

E-ISSN

2573-2293

DOI

10.26434/chemrxiv-2024-ldvx9

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