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Development and characterization of phospho-ubiquitin antibodies to monitor PINK1-PRKN signaling in...

Development and characterization of phospho-ubiquitin antibodies to monitor PINK1-PRKN signaling in...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2915432597

Development and characterization of phospho-ubiquitin antibodies to monitor PINK1-PRKN signaling in cells and tissue

About this item

Full title

Development and characterization of phospho-ubiquitin antibodies to monitor PINK1-PRKN signaling in cells and tissue

Publisher

United States: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2024-01

Language

English

Formats

Publication information

Publisher

United States: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

The selective removal of dysfunctional mitochondria, a process termed mitophagy, is critical for cellular health and impairments have been linked to aging, Parkinson disease, and other neurodegenerative conditions. A central mitophagy pathway is orchestrated by the ubiquitin (Ub) kinase PINK1 together with the E3 Ub ligase PRKN/Parkin. The decorati...

Alternative Titles

Full title

Development and characterization of phospho-ubiquitin antibodies to monitor PINK1-PRKN signaling in cells and tissue

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2915432597

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2915432597

Other Identifiers

ISSN

2692-8205

E-ISSN

2692-8205

DOI

10.1101/2024.01.15.575715