Single-molecule chromatin configurations link transcription factor binding to expression in human ce...
Single-molecule chromatin configurations link transcription factor binding to expression in human cells
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Publisher
United States: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
United States: Cold Spring Harbor Laboratory Press
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Contents
The binding of multiple transcription factors (TFs) to genomic enhancers activates gene expression in mammalian cells. However, the molecular details that link enhancer sequence to TF binding, promoter state, and gene expression levels remain opaque. We applied single-molecule footprinting (SMF) to measure the simultaneous occupancy of TFs, nucleos...
Alternative Titles
Full title
Single-molecule chromatin configurations link transcription factor binding to expression in human cells
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TN_cdi_proquest_journals_2921814078
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2921814078
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ISSN
2692-8205
E-ISSN
2692-8205
DOI
10.1101/2024.02.02.578660
