Discovery of a Novel Mutant-Selective Epidermal Growth Factor Receptor Inhibitor Using in silico Ena...
Discovery of a Novel Mutant-Selective Epidermal Growth Factor Receptor Inhibitor Using in silico Enabled Drug Discovery Platform
About this item
Full title
Author / Creator
Igawa, Hideyuki , Konst, Zef A. , Therrien, Eric , Shelley, Mee , Koldsø, Heidi , Bos, Pieter H. , Negri, Ana , Verras, Andreas , Guo, Jiaye , Dahlgren, Markus , Levinson, Adam , Parr, Brendan T. , Kurhade, Suresh E. , Latthe, Prashant , Shetty, Rajesha , Santhanakrishnan, Sridhar , Amberg-Johnson, Katherine , Futran, Alan , Atsriku, Christian , Pelletier, Robert , Liu, Zhijian , Bell, Jeffery A. , Bhat, Sathesh , Svensson, Mats and Gerasyuto, Aleksey I.
Publisher
Washington: American Chemical Society
Journal title
Language
English
Formats
Publication information
Publisher
Washington: American Chemical Society
Subjects
More information
Scope and Contents
Contents
Despite the success of first, second and third generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in treatment of non-small cell lung cancer (NSCLC) with classical EGFR mutations (L858R or Exon 19 deletions), disease progression often occurs due to the acquisition of additional mutations in the EGFR kinase domain t...
Alternative Titles
Full title
Discovery of a Novel Mutant-Selective Epidermal Growth Factor Receptor Inhibitor Using in silico Enabled Drug Discovery Platform
Authors, Artists and Contributors
Author / Creator
Konst, Zef A.
Therrien, Eric
Shelley, Mee
Koldsø, Heidi
Bos, Pieter H.
Negri, Ana
Verras, Andreas
Guo, Jiaye
Dahlgren, Markus
Levinson, Adam
Parr, Brendan T.
Kurhade, Suresh E.
Latthe, Prashant
Shetty, Rajesha
Santhanakrishnan, Sridhar
Amberg-Johnson, Katherine
Futran, Alan
Atsriku, Christian
Pelletier, Robert
Liu, Zhijian
Bell, Jeffery A.
Bhat, Sathesh
Svensson, Mats
Gerasyuto, Aleksey I.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_3070784725
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3070784725
Other Identifiers
E-ISSN
2573-2293
DOI
10.26434/chemrxiv-2024-5rzt9-v2
