LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development
LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development
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Author / Creator
Adami, Anita , Garza, Raquel , Gerdes, Patricia , Johansson, Pia A , Dorazehi, Fereshteh , Koutounidou, Symela , Castilla-Vallmanya, Laura , Diahann Am Atacho , Sharma, Yogita , Johansson, Jenny G , Tam, Oliver , Kirkeby, Agnete , Barker, Roger A , Molly Gale Hammell , Douse, Christopher H and Jakobsson, Johan
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Long interspersed nuclear element 1 (L1) retrotransposons represent a vast source of divergent genetic information. However, mechanistic analysis of whether and how L1s contribute to human developmental programs is lacking, in part due to the challenges associated with specific profiling and manipulation of human L1 expression. Here we show that th...
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Full title
LINE-1 retrotransposons regulate the exit of human pluripotency and early brain development
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TN_cdi_proquest_journals_3156666589
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3156666589
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E-ISSN
2692-8205
DOI
10.1101/2025.01.17.633315
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https://www.proquest.com/docview/3156666589?pq-origsite=primo&accountid=13902
