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IDH mutations predict longer survival and response to temozolomide in secondary glioblastoma

IDH mutations predict longer survival and response to temozolomide in secondary glioblastoma

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3159103398

IDH mutations predict longer survival and response to temozolomide in secondary glioblastoma

About this item

Full title

IDH mutations predict longer survival and response to temozolomide in secondary glioblastoma

Publisher

Oxford, UK: Blackwell Publishing Ltd

Journal title

Cancer science, 2012-02, Vol.103 (2), p.269-273

Language

English

Formats

Publication information

Publisher

Oxford, UK: Blackwell Publishing Ltd

More information

Scope and Contents

Contents

Recent studies have shown that isocitrate dehydrogenase1/2 (IDH1/2) mutations occur frequently in secondary glioblastoma. This study aimed to investigate their impact on temozolomide chemosensitivity and relationship with O(6)‐methylguanine DNA methyltransferase (MGMT) promoter methylation in secondary glioblastoma. Searches for IDH1 and IDH2 mutat...

Alternative Titles

Full title

IDH mutations predict longer survival and response to temozolomide in secondary glioblastoma

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_3159103398

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3159103398

Other Identifiers

ISSN

1347-9032

E-ISSN

1349-7006

DOI

10.1111/j.1349-7006.2011.02134.x

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