Metabolic Adaptations Rewire CD4 T Cells in a Subset-Specific Manner in Human Critical Illness with...
Metabolic Adaptations Rewire CD4 T Cells in a Subset-Specific Manner in Human Critical Illness with and without Sepsis
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United States: Cold Spring Harbor Laboratory Press
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Language
English
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United States: Cold Spring Harbor Laboratory Press
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Contents
Host immunity in sepsis has features of hyperinflammation together with progressive immunosuppression, particularly among CD4 T cells, that can predispose to secondary infections and ineffectual organ recovery. Metabolic and immunologic dysfunction are archetypal findings in critically ill patients with sepsis, but whether these factors are mechani...
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Metabolic Adaptations Rewire CD4 T Cells in a Subset-Specific Manner in Human Critical Illness with and without Sepsis
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TN_cdi_proquest_journals_3161300705
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3161300705
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ISSN
2692-8205
E-ISSN
2692-8205
DOI
10.1101/2025.01.27.635146