CPSF6 Promotes HIV-1 Preintegration Complex Function
CPSF6 Promotes HIV-1 Preintegration Complex Function
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Author / Creator
Chaudhuri, Evan , Jang, Sooin , Chakraborty, Rajasree , Radhakrishnan, Rajalingam , Arnarson, Bjarki , Prakash, Prem , Cornish, Daphne , Rohlfes, Nicholas , Singh, Parmit K , Shi, Jiong , Aiken, Christopher , Campbell, Edward M , Hultquist, Judd F , Engelman, Alan , Balasubramaniam, Muthukumar and Dash, Chandravanu
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Cleavage and polyadenylation specificity factor 6 (CPSF6) is part of the cellular cleavage factor I mammalian (CFIm) complex that regulates mRNA processing and polyadenylation. CPSF6 also functions as a HIV-1 capsid (CA) binding host factor and promotes viral DNA integration targeting into gene dense regions of the host genome. However, the effects...
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Full title
CPSF6 Promotes HIV-1 Preintegration Complex Function
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TN_cdi_proquest_journals_3161300722
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_3161300722
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E-ISSN
2692-8205
DOI
10.1101/2025.01.28.635394
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https://www.proquest.com/docview/3161300722?pq-origsite=primo&accountid=13902
